NGHIÊN CỨU TỈ LỆ TIỂU CẦU/LYMPHO BÀO VÀ MỐI LIÊN QUAN VỚI KẾT QUẢ TÁI THÔNG ĐỘNG MẠCH VÀNH Ở BỆNH NHÂN NHỒI MÁU CƠ TIM CẤP ST CHÊNH LÊN TẠI BỆNH VIỆN HỮU NGHỊ ĐA KHOA NGHỆ AN

Abstract

Objective: To investigate the association between platelet-to-lymphocyte ratio (PLR) and certain outcomes of percutaneous coronary intervention (PCI) in patients with ST-elevation myocardial infarction (STEMI). Materials and Methods: A cross-sectional descriptive study on 110 patients diagnosed with STEMI and treated with PCI at Nghe An General Hospital from January to September 2024. Data collected included clinical and paraclinical characteristics, PLR at admission and post-PCI, PCI-related indices, and in-hospital major adverse cardiovascular events (MACE). Statistical analysis included appropriate tests, univariate and multivariate logistic regression. Results: Mean age was 68.8 years; 64.6% were male. Median baseline PLR was 158.6 (IQR 90.9–188.8); PLR ≥150 accounted for 51.8%. There was no significant difference between PLR and complete reperfusion after PCI. The in-hospital MACE rate was 24.5% (mainly heart failure 21.8%). On univariate regression, pre-PCI PLR (OR 1.003; p=0.048) and post-PCI PLR (OR 1.008; p=0.008) were associated with MACE. However, multivariate regression retained independent predictors: age (OR 1.078; p=0.013), EF <40% (OR 3.902; p=0.045), and proBNP (OR ≈1.001; p=0.015); Conclusion: PLR reflects the inflammatory-thrombotic status and is associated with MACE at the univariate level but is not an independent prognostic factor after adjustment for age, EF, and proBNP. PLR may be useful as a complementary risk-screening index but cannot replace established clinical and paraclinical measures.