UTILIZATION OF NAPPA-QoL AND NPQ10 INSTRUMENTS FOR EVALUATING QUALITY OF LIFE IN PATIENTS WITH NAIL PSORIASIS
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Abstract
Objective: To assess the quality of life (QoL) of nail psoriatic patients using the NAPPA-QoL questionnaire and NPQ10 scale. Methods: A cross-sectional study on 351 adults with nail psoriasis was conducted at three tertiary hospitals in Ho Chi Minh City between September 2024 and June 2025. Results: The median age was 53 years, with a male-to-female ratio of 2.1:1. The duration of nail psoriasis was 5 years (IQR: 2-10). The median NAPSI score was 48, which was significantly higher in males and patients with longer disease durations (p < 0.001). QoL was impaired in 92.6% and 80.6% of patients based on NAPPA-QoL and NPQ10, respectively. The NAPPA-QoL score was 1.1 (IQR: 0.6-1.5) and the NPQ10 score was 20 (IQR: 5-40). Greater QoL impairment was observed in patients aged 41-60, with psoriatic arthritis, and not receiving biologic therapy. While NAPPA-QoL scores did not differ significantly between genders, NPQ10 scores were higher in males (p = 0.016). Both tools showed strong correlation with NAPSI, the number of affected nails, and DLQI (p < 0.001). Conclusion: Nail psoriasis remarkedly impairs patients’ QoL. Comprehensive management should address both clinical severity and psychosocial burden, supported by the routine use of validated tools such as NAPPA-QoL and NPQ10
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Keywords
quality of life, QoL, NAPPA-QoL, NPQ10, nail psoriasis.
References
2. Augustin M, Blome C, Costanzo A, et al. Nail Assessment in Psoriasis and Psoriatic Arthritis (NAPPA): development and validation of a tool for assessment of nail psoriasis outcomes. Br J Dermatol. Mar 2014;170(3):591-8. doi:10.1111/ bjd.12664
3. Khare S, Agrawal S. Clinico-Epidemiological Characteristics and Impact on Quality of Life in Psoriatic Patients with and without Nail Changes - A Nepalese Experience. Journal of Evidence Based Medicine and Healthcare. 02/08 2021;8:306-312. doi:10.18410/jebmh/2021/60
4. Klaassen KM, van de Kerkhof PC, Pasch MC. Nail psoriasis: a questionnaire-based survey. Br J Dermatol. Aug 2013;169(2): 314-9. doi:10.1111/ bjd.12354
5. Kyriakou A, Patsatsi A, Sotiriadis D. Quality of life and severity of skin and nail involvement in patients with plaque psoriasis. European Journal of Dermatology. 09/01 2014;24(5):623-625. doi:10.1684/ejd.2014.2399
6. Ortonne JP, Baran R, Corvest M, Schmitt C, Voisard JJ, Taieb C. Development and validation of nail psoriasis quality of life scale (NPQ10). J Eur Acad Dermatol Venereol. Jan 2010; 24(1): 22-7. doi:10.1111/j.1468-3083.2009. 03344.x
7. Raposo I, Torres T. Nail psoriasis as a predictor of the development of psoriatic arthritis. 10.1016/j.adengl.2015.02.001. Actas Dermo-Sifiliográficas. 2015;106(6):452-457. doi:10.1016/ j.adengl.2015.02.001
8. Schons KR, Beber AA, Beck Mde O, Monticielo OA. Nail involvement in adult patients with plaque-type psoriasis: prevalence and clinical features. An Bras Dermatol. May-Jun 2015;90(3): 314-9. doi:10.1590/abd1806-4841. 20153736