NHẬN XÉT MỘT SỐ ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG VÀ KẾT QUẢ ĐIỀU TRỊ U ĐỆM DÂY SINH DỤC BUỒNG TRỨNG TẠI BỆNH VIỆN K

Abstract

Purpose: We aimed to assess the clinical features, treatment strategy and outcome of ovarian sex cord-stromal tumors (SCSTs). Materials and Methods: Medical records of 72 casesdiagnosed SCSTs on from 2016 through 2020 in Vietnam National Cancer Hospital were reviewed retrospectively. Results: patients with mean age of 51.6±15.7were reviewed. The most common subtypes were granulosa cell tumors (GCTs) and thecoma-fibroma groups. The mean diameter of the tumor was 11.6 cm (range: 3.5-25cm). The majority of ovarian GCTs were diagnosed at anearly stage (69.2%) and 19.2% and 11.5% for stage II and III, respectively. For a median follow up of 37.0 months (range 8.6-69.6 months), the 5-year overall-survival (OS) and disease-free-survival (DFS) rates were 83.3% and 67.7% respectively. Advanced stage and residual tumor werepoor prognosis factors in patient with ovarian GCTs (p<0.05). Conclusion: SCSTs are uncommon ovarian tumors with a wide age range and diverse histological types. The majority malignant subtypesare GCTs which are diagnosed at an early age and have favorable prognosis. Initial stageand residual diseaseare important prognostic factors of this type.