EVALUATING SYMPTOM IMPROVEMENT IN PATIENTS WITH ABSENT CONTRACTILITY USING PROTON PUMP INHIBITORS COMBINED WITH PROKINETICS

Nguyễn Thị Minh Châu1, Đào Việt Hằng1,2,, Đào Văn Long1,2
1 Hanoi Medical University
2 The Institute of Gastroenterology and Hepatology

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Abstract

A longitudinal study was conducted to compare the symptom improvement of patients diagnosed with absent contractility on high-resolution manometry after 1 month using proton pump inhibitors (PPIs) with or without prokinetics. This study included 50 patients between 9/2020 and 6/2021 at Hoang Long Clinic, of which 12 patients received PPI alone, 38 patients received PPI combined withprokinetic treament. The prevalence of female was 58% and the mean age was 48.4 ± 17.7 years. The mean baseline GerdQ score of 2 groups were 5.83 ± 2.79 and 6.68 ± 2.42, the mean baseline FSSG score of 2 groups were10.17 ± 5.34 and 9.55 ± 5.08. There were no differences in GerdQ score and FSSG score before treatmeant between 2 groups. After treatment, there was a significant improvement in GerdQ, FSSG scores in both groups.

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References

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