Article Sidebar
Views pdf: 41
PREVALENCE OF MALASSEZIA FUNGAL, DEMODEX INFECTIONS IN ACNE PATIENTS ATTENDING HANOI DERMATOLOGY HOSPITAL IN 2024
Main Article Content
Abstract
Objective: To assess the prevalence of Malassezia, Demodex infections in acne patients attending Hanoi Dermatology Hospital in 2024. Subject and methods: A cross-sectional descriptive study was conducted on 80 acne patients. All subjects underwent direct microscopic examination for Demodex and KOH testing for Malassezia detection. Results: Among 80 patients, 35% were positive for either Malassezia or Demodex, including 12.5% with Malassezia infection and 22.5% with Demodex; no co-infection was detected. Infections were more frequent in females (75%), patients aged 18–25 years (78.6%), and those with severe acne (75%). Significant associated factors included history of topical corticosteroid use, facial shaving, oily skin, and sensitive skin. Clinical manifestations associated with Malassezia, Demodex infection included pruritus (64.3%), crawling sensation (46.4%), pustules (92.8%), and erythema with scaling (75%). Conclusion: Malassezia, Demodex infections are relatively common in acne patients, especially in severe cases. Screening for these pathogens may provide useful guidance for more effective treatment strategies.
Article Details
Keywords
acne, Malassezia fungal, Demodex.
References
2. Anh N.M., Hai L.P.H., Thu N.T.A. và cộng sự. (2024). Acne status and associated factors among university students: A cross-sectional study. YHCĐ, 65(Tiếng Anh).
3. Vasam M., Korutla S., và Bohara R.A. (2023). Acne vulgaris: A review of the pathophysiology, treatment, and recent nanotechnology based advances. Biochem Biophys Rep, 36, 101578.
4. Zhao Y., Guo N., Xun M. và cộng sự. (2011). Sociodemographic characteristics and risk factor analysis of Demodex infestation (Acari: Demodicidae). J Zhejiang Univ Sci B,12(12), 998–1007.
5. Spatz M. và Richard M.L. (2020). Overview of the Potential Role of Malassezia in Gut Health and Disease. Front Cell Infect Microbiol, 10, 201.
6. Norn M.S. (1971). Demodex folliculorum. Incidence, regional distribution, pathogenicity. Dan Med Bull, 18(1), 14–17.
7. Phạm Thị Bảo Trâm, Phạm Thanh Thảo, và Huỳnh Văn Bá (2023). Nghiên cứu tình hình nhiễm nấm, demodex, đặc điểm lâm sàng và một số yếu tố liên quan của mụn trứng cá tại bệnh viện da liễu cần thơ năm 2021. Tạp chí Da liễu, 38.
8. Akçınar U.G., Ünal E., và Doğruman Al F. (2018). Demodex spp. as a possible aetiopathogenic factor of acne and relation with acne severity and type. Postepy Dermatol Alergol, 35(2), 174–181.
9. Huỳnh Bạch Cúc (2015), Nghiên cứu tình hình nhiễm nấm, Demodex trên người bệnh mụn trứng cá trưởng thành đến khám tại bệnh viện Da Liễu Cần Thơ, Đại học y dược Cần Thơ.
10. Yuan C., Zheng S.-L., Ma Y.F. và cộng sự. (2017). Cleanser use could decrease numbers of Demodex Folliculorum in mild to moderate acne patients. Dermatoendocrinol, 9(1), e1348444.