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Date Published: 02/02/2026
Abstract Views: 58
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DOI: https://doi.org/10.51298/vmj.v558i2.17071
Issue
Vol. 558 No. 2 (2026)
Section
Các bài báo
How to Cite
Đỗ, N. S., Bùi, T. H. G., Bùi, V. H., & Trần, H. T. (2026). EVALUATION OF FLUID RESPONSIVENESS USING HEMODYNAMIC PARAMETERS DERIVED FROM THORACIC ELECTRICAL BIOIMPEDANCE IN SEPTIC SHOCK PATIENTS UNDERGOING THE PASSIVE LEG RAISING MANEUVER. Vietnam Medical Journal, 558(2). https://doi.org/10.51298/vmj.v558i2.17071

EVALUATION OF FLUID RESPONSIVENESS USING HEMODYNAMIC PARAMETERS DERIVED FROM THORACIC ELECTRICAL BIOIMPEDANCE IN SEPTIC SHOCK PATIENTS UNDERGOING THE PASSIVE LEG RAISING MANEUVER

Ngọc Sơn Đỗ, Thị Hương Giang Bùi, Văn Hướng Bùi, Hữu Thông Trần

Main Article Content

Abstract

Objective: To evaluate fluid responsiveness in septic shock patients through hemodynamic parameters measured by thoracic electrical bioimpedance (TEB) during the passive leg raising (PLR) maneuver. Subjects and methods: A cross-sectional descriptive retrospective study was conducted on patients diagnosed with septic shock who required thoracic electrical bioimpedance (TEB) monitoring and underwent the PLR maneuver to evaluate fluid responsiveness at the Center for Critical Care Medicine, Bach Mai Hospital, between August 2024 and August 2025. All septic shock patients were recruited. Data were collected from medical records and research case report forms, and analyzed using SPSS software. Results: Forty-three patients met the inclusion criteria; the fluid responsiveness rate was 34.9%. Clinical characteristics and severity scores (APACHE II, SOFA, VIS, lactate, PCT) did not differ significantly between responders and non-responders (p > 0.05). In the responder group, ΔSV, ΔSVI, ΔCO, ΔCI, ΔFTc, ΔCPI, ΔPEP, ΔLVET, and ΔICON changed significantly compared with the non-responder group (p < 0.01). Receiver-operating characteristic (ROC) analysis showed that the percent change in stroke volume (ΔSV%) had excellent predictive accuracy for fluid responsiveness with an AUC of 0.95; at an optimal cutoff of approximately 9%, sensitivity was 100%, specificity 85.7%, PPV 73.7%, and NPV 100%. Conclusion: Thoracic electrical bioimpedance combined with the passive leg raising maneuver is an effective method for predicting fluid responsiveness in septic shock patients.

Article Details

Keywords

septic shock; thoracic electrical bioimpedance; TEB; passive leg raising; fluid responsiveness.

References

Hotchkiss RS, Moldawer LL, Opal SM, Reinhart K, Turnbull IR, Vincent JL. Sepsis and septic shock. Nat Rev Dis Primer. 2016 Jun 30;2:16045.
2. Monnet X, Shi R, Teboul JL. Prediction of fluid responsiveness. What’s new? Ann Intensive Care [Internet]. 2022 May 28 [cited 2025 Oct 1];12:46. Available from: https://pmc.ncbi.nlm.nih.gov/ articles/PMC9148319/.
3. Li L, Ai Y, Huang L, Ai M, Peng Q, Zhang L. Can bioimpedance cardiography assess hemodynamic response to passive leg raising in critically ill patients. Medicine (Baltimore) [Internet]. 2020 Dec 18 [cited 2025 Oct 1];99(51):e23764. Available from: https://pmc. ncbi.nlm.nih.gov/articles/PMC7748328/.
4. Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, et al. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA. 2016 Feb 23;315(8):801–10.
5. Phạm Xuân Thắng. Đánh giá nghiệm pháp nâng chân thụ động trong dự đoán đáp ứng truyền dịch ở bệnh nhân sốc nhiễm khuẩn thở máy. Luận văn Thạc sĩ Y học. Trường Đại học Y Hà Nội; 2018.
6. Koopmans NK, Stolmeijer R, Sijtsma BC, Beest PA van, Boerma CE, Veeger NJ, et al. Non-invasive assessment of fluid responsiveness to guide fluid therapy in patients with sepsis in the emergency department: a prospective cohort study. Emerg Med J [Internet]. 2021 Jun 1 [cited 2025 Oct 3];38(6):416–22. Available from: https://emj.bmj.com/content/38/6/416.
7. Awadhare P, Patel R, McCallin T, Mainali K, Jackson K, Starke H, et al. Non-invasive Cardiac Output Monitoring and Assessment of Fluid Responsiveness in Children With Shock in the Emergency Department. Front Pediatr [Internet]. 2022 Apr 7 [cited 2025 Oct 3];10. Available from: https://www.frontiersin.org/ journals/pediatrics/articles/10.3389/fped.2022.857106/full
8. Richard JC, Bayle F, Bourdin G, Leray V, Debord S, Delannoy B, et al. Preload dependence indices to titrate volume expansion during septic shock: a randomized controlled trial. Crit Care [Internet]. 2015 Dec 1 [cited 2025 Oct 3];19(1):5. Available from: https://doi.org/10. 1186/s13054-014-0734-3.