Article Sidebar

PDF
Date Published: 12/01/2022
Abstract Views: 504
Views PDF: 292
DOI: https://doi.org/10.51298/vmj.v509i1.1733
Issue
Vol. 509 No. 1 (2021)
Section
Các bài báo
How to Cite
Hữu Duy, N. ., Thị Liên Hương, N. ., & Quỳnh Nga, V. . (2022). PRESCRIPTION OF GUIDELINE-DIRECTED MEDICATION IN OUTPATIENTS WITH SYSTOLIC HEART FAILURE IN HANOI HEART HOSPITAL. Vietnam Medical Journal, 509(1). https://doi.org/10.51298/vmj.v509i1.1733

PRESCRIPTION OF GUIDELINE-DIRECTED MEDICATION IN OUTPATIENTS WITH SYSTOLIC HEART FAILURE IN HANOI HEART HOSPITAL

Nguyễn Hữu Duy1, Nguyễn Thị Liên Hương1, Vũ Quỳnh Nga2,
1 Hanoi University of Pharmacy
2 Hanoi Heart Hospital

Main Article Content

Abstract

Background and objectives: Ministry of Health’s clinical pathways and guideline of ESC emphasize the role of evidence-based prescribing in patients with heart failure. However, recent studies showed the gaps between guideline recommendations and clinical practice in management of heart failure with reduced ejection fraction. This study aimed to analyse the prescription of evidence-based drugs in outpatients with systolic heart failure in Hanoi Heart hospital. Method: A cross-sectional descriptive study of 134 patients with systolic heart failure, using data obtained from medical records in Hanoi Heart hospital. Contraindications and target dose of ACEI/ARB and BB was defined by guidelines of Vietnam’s Ministry of health 2020 and European society of cardiology 2016. Result: The recommended combination of ACEI/ARB and BBs was prescribed to 92.5% of patients., the percentage of prescription which is continued treatment with ACEI/ARB and BB was 17.2% and 23.1%. No patients were prescribed ACEI/ARB or BB with target dose. On the other hand, 84,0 – 88,3% of patients did not reach the maximal tolerated dose of ACEI/ARB or BB. Conclusion: Dose of ACEI/ARB and BB need titrating to the target dose or maximal tolerated dose in order to reduce the mortality and hospitalization in patients with heart failure.

Article Details

Keywords

HFrEF, guideline-directed medication

References

1. Bộ Y tế (2020), Hướng dẫn chẩn đoán và điều trị suy tim mạn tính.
2. Gheorghiade M., Albert N. M., et al. (2012), "Medication dosing in outpatients with heart failure after implementation of a practice-based performance improvement intervention: findings from IMPROVE HF", Congest Heart Fail, 18(1), pp. 9-17.
3. Peters-Klimm Frank, Natanzon Iris, et al. (2012), "Barriers to guideline implementation and educational needs of general practitioners regarding heart failure: a qualitative study", GMS Zeitschrift für Medizinische Ausbildung, 29(3), pp. 46.
4. Ponikowski P., Voors A. A., et al. (2016), "2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure ", Eur J Heart Fail, 18(8), pp. 891-975
5. Komajda M., Cowie M. R., et al. (2017), "Physicians' guideline adherence is associated with better prognosis in outpatients with heart failure with reduced ejection fraction: the QUALIFY international registry", Eur J Heart Fail, 19(11), pp. 1414-1423.
6. Chang H. Y., Wang C. C., et al. (2017), "Gap between guidelines and clinical practice in heart failure with reduced ejection fraction: Results from TSOC-HFrEF registry", J Chin Med Assoc, 80(12), pp. 750-757.