PRESCRIPTION OF GUIDELINE-DIRECTED MEDICATION IN OUTPATIENTS WITH SYSTOLIC HEART FAILURE IN HANOI HEART HOSPITAL

Nguyễn Hữu Duy1, Nguyễn Thị Liên Hương1, Vũ Quỳnh Nga2,
1 Hanoi University of Pharmacy
2 Hanoi Heart Hospital

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Abstract

Background and objectives: Ministry of Health’s clinical pathways and guideline of ESC emphasize the role of evidence-based prescribing in patients with heart failure. However, recent studies showed the gaps between guideline recommendations and clinical practice in management of heart failure with reduced ejection fraction. This study aimed to analyse the prescription of evidence-based drugs in outpatients with systolic heart failure in Hanoi Heart hospital. Method: A cross-sectional descriptive study of 134 patients with systolic heart failure, using data obtained from medical records in Hanoi Heart hospital. Contraindications and target dose of ACEI/ARB and BB was defined by guidelines of Vietnam’s Ministry of health 2020 and European society of cardiology 2016. Result: The recommended combination of ACEI/ARB and BBs was prescribed to 92.5% of patients., the percentage of prescription which is continued treatment with ACEI/ARB and BB was 17.2% and 23.1%. No patients were prescribed ACEI/ARB or BB with target dose. On the other hand, 84,0 – 88,3% of patients did not reach the maximal tolerated dose of ACEI/ARB or BB. Conclusion: Dose of ACEI/ARB and BB need titrating to the target dose or maximal tolerated dose in order to reduce the mortality and hospitalization in patients with heart failure.

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References

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