GIÁ TRỊ CỦA THANG ĐIỂM TIMI VÀ NT-PROBNP TRONG TIÊN LƯỢNG BỆNH NHÂN NHỒI MÁU CƠ TIM KHÔNG ST CHÊNH LÊN ĐƯỢC CAN THIỆP ĐỘNG MẠCH VÀNH QUA DA

Abstract

Objective: To describe the clinical and laboratory characteristics, as well as NT-proBNP levels, in patients with non-ST-segment elevation myocardial infarction (NSTEMI) undergoing primary percutaneous coronary intervention (PCI) at Thai Nguyen Central Hospital. Additionally, to compare the prognostic value of the TIMI score and NT-proBNP in predicting cardiovascular events in these patients. Methods: A descriptive study was conducted on 55 NSTEMI patients who underwent primary PCI at Thai Nguyen Central Hospital from August 2024 to August 2025. Clinical data, laboratory results, NT-proBNP levels at admission, and TIMI scores were collected and analyzed. Results: The mean age of the patients was 70.11 ± 10.67 years, with a female-to-male ratio of 1:1.62. Most patients were admitted due to chest pain (96.4%), with typical angina in 67.3%, while only 3.6% were admitted due to dyspnea. According to Killip classification, 65.5% were class I, and 12.7% were class IV. TIMI risk stratification showed 61.8% of patients were at moderate risk, and 7.3% at high risk. During hospitalization, 12 patients experienced cardiovascular events, including 6 deaths (10.9%), 7 cases of heart failure, 7 arrhythmias (12.7%). The mean NT-proBNP level at admission was 3025.23 pg/mL (range: 50.06–35,000 pg/mL), with a median of 1190.34 pg/mL. Using a cutoff of NT-proBNP ≥ 860 pg/mL and TIMI score ≥ 3.5 at admission, the prediction of cardiovascular events was statistically significant (p < 0.05). Conclusion: NT-proBNP levels and TIMI scores were significantly different between patients with and without cardiovascular events (p < 0.05). NT-proBNP ≥ 860 pg/mL combined with a TIMI score ≥ 3.5 at admission is a strong predictor of adverse cardiovascular events in NSTEMI patients undergoing primary PCI.