CLINICAL AND PARACLINICAL CHARACTERISTICS AND ANTIBIOTIC RESISTANCE PATTERNS IN FEMALE PATIENTS WITH BACTERIAL CYSTITIS AT THE DEPARTMENT OF GENERAL SURGERY, HAI PHONG MEDICINE UNIVERSITY HOSPITAL
Main Article Content
Abstract
Objective: To describe the clinical and paraclinical characteristics of female patients diagnosed with bacterial cystitis at the General Surgery Department, Hai Phong Medicine University Hospital, from August 2024 to February 2025, and to evaluate the antibiotic resistance patterns of causative pathogens. Methods: A total of 43 female patients diagnosed with bacterial cystitis were enrolled from the General Surgery Department, Hai Phong Medicine University Hospital, during the study period. The study was designed as a case series descriptive study. Results: The mean age was 48.7 ± 20 years. Approximately one-third of patients had a history of urinary tract infections (UTIs). Dysuria and urinary frequency were common symptoms, while hematuria, urgency, and suprapubic pain were reported in about 50%, 20–30% of cases, respectively. Daytime urinary frequency was the most prevalent symptom of bladder irritation. Over three-quarters of patients experienced symptom resolution within 3–5 days of treatment. Most patients had hematuria and pyuria on urinalysis, though nitrite positivity was observed in only 10 out of 43 cases. Bladder wall thickening on ultrasound was noted in approximately half of the patients. Regarding microbial profile, Escherichia coli was the most frequently isolated pathogen (32/43), followed by Proteus species (5/43). High resistance rates were found with Beta-lactams and Ciprofloxacin. Aminoglycosides showed good sensitivity, and no resistance was observed to Carbapenems. Conclusion: Cystitis in women commonly presents with irritative voiding symptoms and mucosal inflammation. E. coli remains the predominant pathogen, with high resistance rates to conventional UTI antibiotics.
Article Details
Keywords
urinary tract infection, cystitis, women, antibiotic resistance
References
2. Folliero V., et al., "Prevalence and Antimicrobial Susceptibility Patterns of Bacterial Pathogens in Urinary Tract Infections in University Hospital of Campania "Luigi Vanvitelli" between 2017 and 2018". Antibiotics (Basel), 2020. 9(5).
3. Nguyễn Thị Hồng Minh, Trần Văn Long, "Đặc Điểm Lâm Sàng Và Vi Sinh Vật Học Viêm Bàng Quang Ở Phụ Nữ Cao Tuổi Tại Bệnh Viện Bạch Mai". Tạp chí Y học Thực hành, 2021. 946(2): tr. 112-118.
4. Foxman B., "Recurring urinary tract infection: incidence and risk factors". Am J Public Health, 1990. 80(3): p. 331-333.
5. Grigoryan L., Trautner B.W., Gupta K., "Diagnosis and management of urinary tract infections in the outpatient setting: a review". Jama, 2014. 312(16): p. 1677-84.
6. Ventola C.L., "The antibiotic resistance crisis: part 1: causes and threats". P t, 2015. 40(4): p. 277-83.
7. Đặng Thị Kiều Phương, Trần Thị Việt Hà, "Đặc Điểm Bệnh Nhân Nhiễm Khuẩn Tiết Niệu Phức Tạp Tại Bệnh Viện Bạch Mai". Tạp chí Y học Việt Nam, 2022. 518(2): tr. 279 - 282.
8. Trần Quốc Huy và cộng sự, "Tình Trạng Nhiễm Khuẩn Tiết Niệu Và Kháng Kháng Sinh Tại Bệnh Viện Đa Khoa Tỉnh Kiên Giang Năm 2021". Tạp chí Y học Việt Nam, 2023. 523(1): tr. 256 -261.