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Date Published: 12/01/2022
Abstract Views: 180
Views PDF: 131
DOI: https://doi.org/10.51298/vmj.v509i1.1740
Issue
Vol. 509 No. 1 (2021)
Section
Các bài báo
How to Cite
Thị Linh, N. ., Văn Đoàn, N. ., & Chí Hiếu, C. . (2022). EFFICACY OF INTRAVENOUS HUMAN IMMUNOGLOBULIN IN DRUG – INDUCED TOXIC EPIDERMAL NECROLYSIS. Vietnam Medical Journal, 509(1). https://doi.org/10.51298/vmj.v509i1.1740

EFFICACY OF INTRAVENOUS HUMAN IMMUNOGLOBULIN IN DRUG – INDUCED TOXIC EPIDERMAL NECROLYSIS

Nguyễn Thị Linh1,, Nguyễn Văn Đoàn1, Chu Chí Hiếu2
1 Hanoi Medical University
2 Bach Mai Hospital

Main Article Content

Abstract

Objectives: In this study, we aimed to evaluate the efficacy of intravenous immunoglobulin in patients with drug-induced toxic epidermal necrolysis (TEN). Methods: This was a retrospective study on patients diagnosed as drug-induced TEN at Center of Allergology and clinical immunology, Bach Mai Hospital during the period of April 2019 to July 2020. Results: IVIg was used for treatment in 9 out of 29 cases, the mortality rate in the IVIg group was 0% compared to 10% in the non-IVIG group. There was no statistically significant difference in the average length of hospital stay in the two group (15.33 ± 7,632 days in the IVIg group versus 14.15 ± 4.392 days in the non-IVIg group) Conclusion: IVIg is one of the systemic therapies in the treatment of TEN, however, the effectiveness of treatment is still controversial. Larger and more comprehensive studies are needed to evaluate the efficacy of this method.

Article Details

Keywords

Drug allergy, TEN, IVIg

References

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