SEPSIS AND SEPTIC SHOCK IN THE INFECTIOUS DISEASES INTENSIVE CARE UNIT AT CHILDREN’S HOSPITAL 1 ACCORDING TO THE PHOENIX CRITERIA

Nguyễn Thế Nguyên Phùng, Thị Tâm Phùng

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Abstract

Objective: To describe the clinical characteristics, severity stratification using the Phoenix criteria, and the relationship with outcomes in pediatric patients admitted to the Infectious Diseases Intensive Care Unit. Methods: A cross-sectional descriptive study with prospective follow-up was conducted on all children aged 1 month to under 16 years admitted to the Infectious Diseases ICU at Children’s Hospital 1 from June 2024 to July 2025. Clinical data, laboratory findings, and Phoenix scores were collected and analyzed. Results: Among 197 patients, 73.6% had sepsis and 46.2% developed septic shock. The overall mortality rate was 16.3%. Patients with sepsis had significantly higher Phoenix scores across respiratory, cardiovascular, hematologic, and neurologic domains (p < 0.001). There were no significant differences in age, sex, comorbidities, or initial clinical symptoms between the sepsis and non-sepsis groups. Conclusion: The Phoenix criteria proved effective in stratifying severity and predicting outcomes in pediatric sepsis. Early application may help identify high-risk patients and guide timely interventions to improve survival

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References

1. Schlapbach LJ, Watson RS, Sorce LR, et al. International Consensus Criteria for Pediatric Sepsis and Septic Shock. JAMA. 2024;doi: Published online January 21, 2024. doi:10.1001/jama.2024.0179
2. Phùng Nguyễn Thế Nguyên. Đặc điểm lâm sàng, cận lâm sàng và một số yếu tố tiên lượng tử vong trong sốc nhiễm khuẩn ở trẻ em. Y Học TP Hồ Chí Minh. 2011;15(1):200-088.
3. Bùi Thanh Liêm, Phùng Nguyễn Thế Nguyên, Trần Diệp Tuấn (2019). So sánh tác nhân gây nhiễm trùng huyết qua cấu máu và PCR máu tại khoa Hồi sức tích cực- Chống độc, BV NĐ 1. Y Học TP. Hồ Chí Minh, 23(4), tr. 76-82.
4. Nguyễn Phước Sang, Phùng Nguyễn Thế Nguyên, Trần Diệp Tuấn. Khảo sát đặc điểm các trường hợp bệnh nhi tử vong do sốc nhiễm khuẩn tại bệnh viện Nhi đồng Cần Thơ. Tạp Chí Y Dược học Cần Thơ. 2018;13(1):121-8.
5. Nguyễn Văn Tuy, Đặng Thị Tâm, Bùi Quang Sự, Nguyễn Đắc Lương, Phạm Kiều Lộc. Giá trị tiên đoán của thể tích trung bình tiểu cầu trong chẩn đoán và tiên lượng nhiễm khuẩn huyết ở trẻ em. Tạp chí truyền nhiễm Việt Nam: 2(46):11-17. https://doi.org/10.59873/vjid.v2i46.360
6. Han CH, Kim H, Park M, Kim SY, Kim JD, Sohn MH, You SC, Kim KW. Validation of the Phoenix Criteria for Sepsis and Septic Shock in a Pediatric Intensive Care Unit. J Korean Med Sci. 2025 Mar;40(10): e106. https://doi.org/10.3346/ jkms.2025.40.e106
7. Hadzhieva-Hristova A, Krumova D, Stoeva T, Georgieva R, Iotova V. Assessment of Phoenix Sepsis Score, pSOFA, PELOD-2, and PRISM III in Pediatric Intensive Care. Children. 2025; 12(3):262. https://doi.org/10.3390/children 12030262.
8. Carter, Michael J. et al. Evaluation of Phoenix sepsis score criteria: exploratory analysis of characteristics and outcomes in an emergency transport PICU cohort from the United Kingdom, 2014–2016. Pediatr Crit Care Med. 2025;26(2): e186-e196; doi: https://doi.org/10.1097/PCC. 0000000000003682