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Date Published: 05/05/2021
Abstract Views: 321
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DOI: https://doi.org/10.51298/vmj.v498i2.176
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Vol. 498 No. 2 (2021)
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Việt Hằng, Đào, Ngọc Minh, T., Thị Thu Trang, T. ., & Văn Long, Đào. (2021). PRELIMINARY RESULT OF NEUROENDOCRINE TUMOUR RESECTION USING FLEXIBLE ENDOSCOPY. Vietnam Medical Journal, 498(2). https://doi.org/10.51298/vmj.v498i2.176

PRELIMINARY RESULT OF NEUROENDOCRINE TUMOUR RESECTION USING FLEXIBLE ENDOSCOPY

Đào Việt Hằng, Trần Ngọc Minh, Trần Thị Thu Trang, Đào Văn Long

Main Article Content

Abstract

From January 1, 2016 to July 31, 2020, our study collected 25 patients which had 26 tumors with a histological diagnosis of gastrointestinal neuroendocrine tumors (NET). Most tumors located in the rectum (84.6%), originated from the submucosa (61.1%) and were less than 2cm (100%). All tumors had clear delineation and had no lymph nodes. The tumors were removed by snare resection assisted by submucosal injections of 1/10000 adrenaline (73.1%) or by non-assisted snare resection (26.9%). The rate of complete removal was 100%. 24 patients (96.0%) achieved good results, 1 patient (4.0%) had rectal perforation after the intervention and had to undergo laparoscopic surgery for closure. On histopathology, all tumors had typical characteristics of NET. On immunohistochemistry, 8/25 patients showed expressions of several CD56 makers, Chromogranin, CK10, HE, Ki67, Neuron-specific enolase, synaptophysin. Our preliminary study showed that endoscopic resection was effective and safe in the treatment of neuroendocrine tumors

Article Details

Keywords

Neuroendocrine tumors, NET, carcinoid, endoscopic resection, endoscopic mucosal resection, EMR

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