PROGNOSTIC FACTORS OF PRETERM BIRTH AFTER LASER UMBILICAL CORD ABLATION FOR TWIN-TWIN TRANSFUSION SYNDROME AT HANOI OBSTETRICS AND GYNECOLOGY HOSPITAL

Phan Thị Huyền Thương1,2,, Nguyễn Duy Ánh1,2, Hồ Sỹ Hùng2, Nguyễn Thị Sim1, Nguyễn Thị Thu Hà1, Trương Quang Vinh3
1 Hanoi Obstetrics and Pediatrics Hospital
2 Department of Obstetrics and Gynecology, Hanoi Medical University
3 University of Medicine and Pharmacy, Vietnam National University, Hanoi

Main Article Content

Abstract

Objectives: To evaluate the prognostic factors to the risk of preterm birth after laser umbilical cord ablation in the treatment of twin-twin transfusion syndrome (HCTMST). Methods: This was a prospective study, data collected from October 2019 to November 2020 at Fetal Medicine center in HOGH. Twenty-one twins with a diagnosis of  HCTMST stage II, III, IV before 26 gestations according to Quintero classification performed selected umbilical cord laser ablation. Results: The mean gestational age at birth was 34,70 ± 4,33 weeks, the average time of additional pregnancy retention after surgery was 12,97 weeks. The rate of preterm birth under 37 weeks was over 50%, 31% of premature birth under 34 weeks. The risk of preterm birth before 34 weeks of surgery increased by 4,33 times if the gestational week was more than 22 weeks. Similarly, the risk of preterm birth increased more than 8,67 times if the change in cervical length 48 hours after surgery was more than 9,5%. The survival rate of newborns after surgery was 90,48%. There were 2 stillbirths within 7 days after the operation, accounting for 6,06%, no intraoperative complications, and maternal complications after surgery were recorded. Conclusion: Gestational week at surgery and change in cervical length 48 hours after surgery are prognostic factors for the risk of preterm delivery after surgery.

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References

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