CLINICAL AND PARACLINCAL FEATURES OF LOCALLY ADVANCED GASTRIC CANCER INVADING DUODENUM, HEAD OF PANCREAS AND HEPATO-DUODENAL LIGAMENT
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Abstract
Aime of study: Retrospective study aim at Evaluating the Epidemiology and Clinical and Paraclinical features of Locally Advanced Gastric Cancer Invading Duodenum, Head of pancreas or Hepato-Duodenum ligament. Rersults: There were 40 patients, mean age: 63,08±1,73 Y, male 82,5%, Female 17,5%, Sex ratio 4,7. Medical history: gastro-duodenal ulcer in 47,5%; Comorbidities in 72,5%. Clinical and paraclinic features: Epigastric pain in 100%; Melena in 62,5%; Gastric outlet obstruction in 85,0%. Weight loss in 82,5%; Panpable tumor in 27,5%. Distal gastric cancer in 100%: Among them, pyloric tumor in 25%; Antral-pyloric tumor in 52,5%; Antral tumor in 7,5%; Antral tumor invaded lesser curvature in 15%. Tumor diameter ≤ 5 cm in 60%. Gastric outlet obstruction (by gastro duodenal scopy ) in 42,5%. CTScan revealed tumor invaded duodenum or head of pancreas in 15%. Pathological resuls: poorly differentiated carcinoma in 47,5%; Moderately differentiated carcinoma in 27,5 %;signet Ring Cell carcinoma 20%; Mucinous adenocarcinoma in 5%. Conclusions: 1.The common features: Mean age 63,08±1,73 Y; male 82,5%, Female 17,5%, Sex ratio 4,7. Medical history: gastro-duodenal ulcer in 47,5%; Comorbidities in 72,5%. 2. Clinical and paraclinical features: Epigastric pain in 100%; Melena in 62,5%; Gastric outlet obstruction in 85,0%. Weight loss in 82,5%; Panpable tumor in 27,5%. Tumor location (gastroduodenal finding) : Distal gastric cancer in 100%: Among them, pyloric tumor in 25%; Antral-pyloric tumor in 52,5%; Antral tumor in 7,5%; antral tumor invaded lesser curvature in 15%. Tumor diameter ≤ 5 cm in 60%. Pylory stricture (by gastro duodenal scopy ) in 42,5%. CTScan finding (Preoperative): Tumor invaded duodenum or head of pancreas in 15%. Pathological resuls: Poorly differentiated Carcinoma in 47,5%; Moderately differentiated Carcinoma in 27,5 %;signet Ring Cell Carcinoma 20%; Mucinous Adenocarcinoma in 5%.
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