ĐÁNH GIÁ KẾT QUẢ SỬ DỤNG CÁC THUỐC ĐIỀU TRỊ NỀN TẢNG TRONG ĐIỀU TRỊ BỆNH NHÂN SUY TIM PHÂN SUẤT TỐNG MÁU GIẢM ĐIỀU TRỊ NGOẠI TRÚ TẠI BỆNH VIỆN ĐA KHOA TỈNH THANH HOÁ

Abstract

Objectives: (1) Describe the characteristics of outpatients with heart failure with reduced ejection fraction (HFrEF) treated at Thanh Hoa General Hospital. (2) Evaluate the outcomes of using foundational therapies in the treatment of HFrEF at the outpatient clinic of Thanh Hoa General Hospital. Subjects and Methods: A cross-sectional descriptive study was conducted on 1,100 heart failure patients, including 50 patients with HFrEF treated as outpatients from March 2025 to September 2025. Results: the 1,100 heart failure outpatients:  NYHA class II was 46.1%, NYHA class IV was 6.6%, coronary artery disease (54.6%), hypertension (42.5%). the 50 HFrEF patients treated with the four pillars, NYHA class III (86%), no patients in NYHA class I or IV. The mean ejection fraction (EF) was 30.8 ± 6.4%, the mean proBNP level was 4364.1 ± 548.1 pg/mL. After 3 months, no patients remained in NYHA class III; after 6 months, 90% of patients were classified as NYHA class I. Both EF and proBNP levels showed significant improvement over the 6-month follow-up period (p < 0.05). No adverse drug reactions were recorded during the study period. Conclusion: The four pillars therapies in patients with HFrEF in this study resulted in significant improvements in NYHA functional class, EF, and serum proBNP levels, with no adverse effects reported during the study period