HIGH- RISK HPV INFECTION IN PATIENTS WITH ABNORMAL CERVICAL VAGINAL CELLS AT THE NATIONAL HOSPITAL OF OBSTETRICS AND GYNECOLOGY

Ngô Thị Thanh Hương1,, Đào Thị Hoa2, Lê Hoàng3
1 Bac Ninh Obstetrics and Pediatrics Hospital
2 National Hospital of Obstetrics and Gynecology
3 Tâm Anh Hospital

Main Article Content

Abstract

Objective: Determine the prevalence of high-risk HPV infection in patients with abnormal cervical vaginal cells and compare high- risk HPV results with abnormal cervical vaginal cytology results. Material and Methodology: Study on 259 women who visited the examination department at the National Hospital of Obstetrics and Gynecology with high- risk HPV test and abnormal cervical cell results during the period from 8/ 2020 to 4/2021. Result: The average age of women talking the test was 38± 9,1; the highest number of women aged 25 – 39 accounted for 52,9%. There were 76,4 % cases of HPV infection in which: 37,1% infected with 1/12 other high-risk types accounted for the highest rate; 17,8% infected with Type 16; 6,2% infected with Type 18; 15,4% infected with 2 or more types. The percentage of abnormal cervical cells: 0,8% is squamous cell carcinoma; 42,9% had the highest percentage of LSIL lesions; 18,5% is HSIL; 34,4% were reactive cells (ASC: 30,5% and AGC: 3,9%). There were 69,6% ASCUS cells infected with HPV; 85,6% of LSIL cells infected with HPV; 83,1% of HSIL had HPV infection and both squamous cell carcinoma cases were not infected with HPV.

Article Details

References

1. Bruni L B-RL, Albero G, Aldea M, Serrano B, Valencia S, Brotons M, Mena M, Cosano R, Munoz J, Bosch FX, de Sanjose' S, Castellsague' X. Human Papilomavirus and Related Diseases in the World, Catalan Insitute of Oncology Information Centre on HPV and Cancer.
2. Bộ y tế-Vskbmt. Kế hoạch hành động quốc gia dự phòng và kiểm soát ung thư cổ tử cung giai đoạn 2016-2025. 2016.
3. Lê Quang Vinh LTH. Phát hiện tỉ lệ nhiễm HPV và tế bào cổ tử cung bất thường ở phụ nữ Thái Nguyên. Tạp chí nghiên cứu y học. 2013;3.
4. Trương Quang Vinh. Nghiên cứu nhiễm Human Papilloma virus ở các phụ nữ có các tổn thương tiền ung thư và ung thư cổ tử cung, . Trường Đại học Y Dược, Đại học Huế. 2010.
5. J. Thomas Cox MPEC, PhD, MPH; Catherine M. Behrens, MD, PhD; Abha Sharma, PhD;Thomas C. Wright Jr, MD; Jack Cuzick, PhD;. and the Athena HPV Study Group, (2012), Comparison of cervical cancer screening strategies incorporating different combinations of cytology, HPV testing, and genotyping for HPV 16/18: results from the ATHENA HPV study. American Journal of Obstetrics and Gynecology 2012.
6. Phạm Thị Ngọc Xuân TTL. Tầm soát ung thư cổ tử cung tại các xã huyện Thủ Thừa tỉnh Long An. Tạp chí y học thành phố Hồ Chí Minh. 2008;1:12.
7. NatachaPhoolcharoen N, ThaniyaSricharunrat, SiripornSaeloo, WaraphornKrongthong (2017). A population-based study of cervical cytology findings and human papillomavirus infection in a suburban area of Thailand. Gynocologic oncology report. 2017;21:73.
8. Nguyễn Thị Hồng Nga. Khảo sát mối liên quan giữa nhiễm HPV nguy cơ cao với các tổn thương tiền ung thư và ung thư cổ tử cung tại bệnh viện phụ sản trung ương. Đại học Y Hà Nội 2017.