OUTCOMES OF RETROPERITONEOSCOPIC SURGERY FOR THE TREATMENT OF ADRENAL TUMORS AT E HOSPITAL

Đình Liên Nguyễn 1,2, Thị Mỹ Dung Đinh 1, Thị Thi Hồng Vũ 1, Xuân Trường Bùi 1,
1 E Hospital
2 University of Medicine and Pharmacy, Vietnam National University, Hanoi

Main Article Content

Abstract

Objective: To describe the clinical and paraclinical characteristics and to evaluate the surgical outcomes of retroperitoneoscopic adrenal tumor resection; to compare surgical outcomes between total adrenalectomy and adrenal-sparing surgery; and to investigate several factors related to the feasibility of adrenal preservation. Methods: A cross-sectional descriptive study. Results: A total of 32 patients undergoing retroperitoneoscopic adrenal tumor resection were included in the study. The mean age was 48.9 ± 15.8 years, with no significant difference in sex distribution. Most patients were incidentally diagnosed or presented with hypertension, accounting for 84.4%. The mean tumor size was 3.5 ± 2.2 cm, the mean operative time was 76.6 ± 15.3 minutes. Intraoperative and postoperative outcomes, including operative time, length of hospital stay, duration of drainage, estimated blood loss, and complication rates, were comparable between the total adrenalectomy group and the adrenal-sparing group, with no statistically significant differences (p > 0.05). Conclusion: Retroperitoneoscopic surgery is a safe, minimally invasive, and effective approach for the treatment of adrenal tumors. Short-term outcomes suggest that adrenal-sparing surgery is technically feasible and provides comparable intraoperative and postoperative clinical results to total adrenalectomy in the management of adrenal tumors. Further large-scale randomized controlled studies are required to further validate the safety and efficacy of these two approaches.

Article Details

References

1. Zeiger Ma, Thompson Gb, Duh Qy, et al. American Association of Clinical Endocrinologists and American Association of Endocrine Surgeons Medical Guidelines for the Management of Adrenal Incidentalomas: executive summary of recommendations. Endocr Pr 2009 Jul-Aug155450-3 Doi 104158EP155450 PMID 19632968.
2. Alemanno G, Bergamini C, Prosperi P, Valeri A. Adrenalectomy: indications and options for treatment. 2017. https://pubmed.ncbi.nlm.nih.gov/28421470/
3. Gagner M, Lacroix A, Bolté E. Laparoscopic adrenalectomy in Cushing’s syndrome and pheochromocytoma. PubMed. Published online 1992. Accessed June 25, 2025. https://pubmed.ncbi.nlm.nih.gov/1387700/
4. Mercan S, Seven R, Ozarmagan S, Tezelman S. Endoscopic retroperitoneal adrenalectomy. 1995. Accessed June 25, 2025. https://pubmed.ncbi.nlm.nih.gov/7491525/
5. Sergiy P Styopushkin, Viktor P Chaikovskyi, et al. Partial laparoscopic adrenalectomy - anatomical basis and operation technique. PubMed. Accessed January 1, 2026. https://pubmed.ncbi.nlm.nih.gov/33148844/
6. Jian Hu Liu, Xue Dong Wei, et al. Long-Term Results of Laparoscopic Partial Versus Total Adrenalectomy for Aldosterone Producing Adenoma. PubMed. Published online 2020. Accessed January 1, 2026. https://pubmed.ncbi.nlm.nih.gov/32309875/
7. Kong W, Zhang N, Li H, Hong B, Zhao J, Zhang N. A propensity score analysis of outcome in retroperitoneal laparoscopic partial versus total adrenalectomy: a cohort study. Ann Laparosc Endosc Surg. 2025;10(0). doi:10.21037/ales-24-61
8. Corssmit Epm, Dekkers Om. Screening in adrenal tumors. 2019 May313243-246 Doi 101097CCO0000000000000528 PMID 30844886.
9. Nguyễn Việt Tuấn, Hoàng Long, Võ Văn Minh, Nguyễn Văn Linh. Kết quả phẫu thuật nội soi sau phúc mạc điều trị hội chứng conn do u tuyến thượng thận. Tạp Chí Học Việt Nam. 2023;522(1):1. doi:10.51298/vmj.v522i1.4216
10. Trần Quốc Hoà, Nguyễn Đình Bắc. Kết quả phẫu thuật nội soi sau phúc mạc cắt u tuyến thượng thận có tăng tiết hormone. 2023. Tạp chí nghiên cứu y học 270 tcncyh 170 (9)-2023.
11. Vũ Văn Hà, Lê Huy Bình, Nguyễn Ngọc Sơn, Hoàng Long. Kết quả phẫu thuật cắt u tuyến thượng thận qua đường sau phúc mạc tại Bệnh viện Việt Đức. Tạp Chí Học Thành Phố Hồ Chí Minh - 2015. https://tapchiyhoctphcm.vn/articles/14327
12. Giordano WC. Preservation of Adrenocortical Function During Surgery for Bilateral Pheochromocytoma. J Urol. Published online January 1982. doi:10.1016/S0022-5347(17)53627-7
13. Long-term outcome of retroperitoneoscopic partial versus total adrenalectomy in patients with Cushing’s syndrome - PubMed. Accessed January 25, 2026. https://pubmed.ncbi.nlm.nih.gov/38651548/
14. Miyamoto S, Nakao J, Higashino T, Yoshimoto S, Hayashi R, Sakuraba M. Clavien–Dindo classification for grading complications after total pharyngolaryngectomy and free jejunum transfer. PLoS ONE. 2019;14(9):e0222570. doi:10.1371/journal.pone.0222570