PROSPECTIVE VALUE OF PRE-ECLAMPSIA, ECLAPMSIA OF PlGF AND PAPP-A IN THE RISK GROUP AT HAI PHONG OBSTETRICS AND GYNECOLOGY HOSPITAL

Lưu Vũ Dũng1,2,, Phạm Thị Thu Trang2, Vũ Văn Tâm1,2
1 Hai Phong Obstetrics and Pediatrics Hospital
2 Haiphong University of Medicine and Pharmacy

Main Article Content

Abstract

Purpose: Investigate the prognostic value of pre-eclampsia and eclampsia of PlGF and PAPP-A test in risk group at Haiphong Obstetrics and Gynecology Hospital (07/2019- 09/2020). Subjects and methods: 170 pregant women with pre-eclampsia risk diagnosed who came to the examination, management of pregnancy at Hai Phong Obstetrics and Gynecology Hospital. Cross-sectional, retrospective description. Results: 16/70 cases were positive for the predictive test for pre-eclampsia, accounting for 9,4%. The mean value of PAPP-A of the pre-eclampsia group was 2,23 ± 0,59, the cut-off of the predictive value of PAPP-A was 2,45 MOM, sensitivity: 66,7%, specificity: 75,5%. The group with PAPP-A value <2,45 MOM had 1 6,1 times greater risk of pre-eclampsia. The mean value of PlGF of the pre-eclampsia group was 38,3 ± 10, the cut-off of the predictive value of PlGF was <35,5 pg/ml, sensitivity: 66,7%, specificity: 78,4%. The group with PlGF value <35,5 pg/ml had 1 6,7 times greater risk of pre-eclampsia. Conclusions: The group with PAPP-A value <2,45 MOM had 1 6,1 times greater risk of pre-eclampsia. The group with PlGF value <35,5 pg/ml had 1 6,7 times greater risk of pre-eclampsia.

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References

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