KHẢO SÁT TỶ LỆ HỒI PHỤC THỊ LỰC TRONG BỆNH LÝ VIÊM MŨI XOANG DO NẤM XÂM LẤN

Abstract

Introduction: Acute invasive fungal sinusitis (AIFS) is a severe infectious disease with multiple dangerous complications, particularly in immunocompromised patients. Ocular complications, including vision loss and ophthalmoplegia, are among the most serious clinical manifestations, directly affecting quality of life after treatment. While previous studies have primarily focused on survival rates, data regarding the recovery of visual function in Vietnam remain limited. The relationship between causative pathogens, timing of intervention, and the severity of initial damage with visual outcomes requires further investigation. Objective: To compare epidemiological characteristics, microbiological agents, and clinical damage between patients with complete vision loss and those with partial visual impairment. To evaluate the rate of visual recovery after treatment in each group of patients with acute invasive fungal sinusitis at the University Medical Center Ho Chi Minh City from 2022 to 2025. Materials and Methods: A retrospective study was conducted on 30 AIFS patients with ocular complications at University Medical Center Ho Chi Minh City between 2022 and 2025. Patients were categorized into Group 1 (complete vision loss) and Group 2 (partial vision loss). Outcomes were assessed at 1-month follow-up. Results: Group 1 (n=12) showed a significantly higher prevalence of Mucorales infection (75%) compared to Group 2 (predominantly Aspergillus). Following treatment, 100% of patients in Group 1 showed no visual recovery. Conversely, Group 2 achieved a visual improvement rate of 33.3%. Ocular motility recovery rates were comparable between the two groups (40% and 50%, respectively). Conclusion: Complete vision loss due to Mucorales is a poor prognostic factor for visual outcomes. Aggressive intervention within the "golden window" is essential for patients with partial vision loss to enhance the potential for visual recovery.