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Date Published: 13/01/2022
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Views PDF: 187
DOI: https://doi.org/10.51298/vmj.v509i2.1829
Issue
Vol. 509 No. 2 (2021)
Section
Các bài báo
How to Cite
Quang Chiêm, L. ., Đức Bình, V. ., & Thị Minh Nguyệt, N. . (2022). CLINICAL AND SUBCLINICAL FEATURES OF MARGINAL ZONE LYMPHOMA (MZL) AT THE NATIONAL INSTITUTE OF HEMATOLOGY AND BLOOD TRANSFUSION. Vietnam Medical Journal, 509(2). https://doi.org/10.51298/vmj.v509i2.1829

CLINICAL AND SUBCLINICAL FEATURES OF MARGINAL ZONE LYMPHOMA (MZL) AT THE NATIONAL INSTITUTE OF HEMATOLOGY AND BLOOD TRANSFUSION

Lê Quang Chiêm1,, Vũ Đức Bình2, Nguyễn Thị Minh Nguyệt2
1 Hanoi Medical University
2 National Institute of Hematology and Blood Transfusion

Main Article Content

Abstract

Objectives: Todescribethe clinical and subclinical characteristics of patients with Marginal zone lymphoma (MZLs) at the National Institute of Hematology and Blood Transfusion from January 2015 to October 2021.  Methods: A cross-sectional study was implemented among 86 MZLspatients. Results: All 3 types including MALT (73.3%), NMZL (20.9%) and SMZL (5.8%) were found in our study; the more common affected locationswere the stomach (25.6%) and the eyes (24.4%). The proportion of men was higher than women (58.1% and 41.9%, respectively). The mean age of MALT, NMZL and SMZL patients were 54.6; 52.8 and 55.8 years old, respectively. The incidences of B symptoms (7.9%), anemia (20.6%), lymphadenopathy (1.6%), splenomegaly (0%)in MALT group were statistically lowerthan those in NMZL and SMZL groups.The MALT group also hadthe rates of low hemoglobin concentration (20.6%), low platelet count (4.8%), high white blood cell count (9.5%), myeloid cell morphological disorder (11.1%), increased density of bone marrow cells (7.9 %), bone marrow invasion (11.1%) and positive-Ki67>30% (11.1%) lower than those of NMZL and SMZL groups. There was no histopathological difference between the 3 groups of MZLs. Conclusion: MALT is the most common type of MZLs and has the differences in clinical and subclinicalfeatures in comparison with NMZL and SMZL.

Article Details

Keywords

MALT, NMZL, SMZL, MZL

References

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