HIỆU QUẢ VÀ TÍNH AN TOÀN CỦA PHƯƠNG PHÁP ĐÓNG THÔNG LIÊN THẤT PHẦN MÀNG NGƯỢC CHIỀU BẰNG ĐƯỜNG ĐỘNG MẠCH ĐÙI

Abstract

Objective: To evaluate the safety and effectiveness of transcatheter closure of perimembranous ventricular septal defects via the femoral arterial approach.

Methods: A descriptive study combining prospective and retrospective data with longitudinal follow-up was conducted on 47 patients with ventricular septal defects who underwent transcatheter intervention at Khanh Hoa General Hospital from March 2022 to April 2024.

Results: The mean age was 30.4 months and the mean body weight was 12.6 kg; females accounted for 66.7% of patients. Associated cardiac lesions included patent ductus arteriosus (16.7%), atrial septal defect (4.2%), and ventricular septal aneurysm (8.3%). Twenty-four of 47 patients (51%) met the criteria for retrograde transcatheter closure via the femoral artery. Procedural success was achieved in 23 of 24 cases (95.8%). One unsuccessful case (4.2%) was due to aortic regurgitation after deployment of an ADO II device and was subsequently successfully treated using an antegrade approach with a Piccolo 5/6 device. Complete closure rates were 82.6% immediately after the procedure, 95.7% at 6 months, and 100% at 1-year follow-up. No major complications were observed during or after the procedure.

Conclusion: Retrograde transcatheter closure of perimembranous ventricular septal defects via the femoral arterial approach is a safe, feasible, and effective technique in appropriately selected patients, with high procedural success and a low complication rate during short- and mid-term follow-up.