SURGICAL OUTCOMES OF BRAIN METASTASIS RESECTION UNDER INTRAOPERATIVE ULTRASOUND AT SAINT PAUL HOSPITAL

Trung Kiên Dương1, , Mạnh Hùng Nguyễn1, Việt Đức Nguyễn1,2, Ngọc Anh Vũ1, Trung Thành Đinh1
1 Bệnh viện Đa khoa Xanh Pôn
2 Trường Đại học Y Hà Nội

Main Article Content

Abstract

Objective: To evaluate surgical outcomes of brain metastasis resection under intraoperative ultrasound guidance at Saint Paul General Hospital and to discuss the value of intraoperative ultrasound compared with neuronavigation in metastatic brain tumor surgery.


Materials and methods: A case series of 21 patients with brain metastases operated on with intraoperative ultrasound guidance. Data included demographics, clinical presentation, imaging findings, extent of resection, pre- and postoperative Karnofsky Performance Status, complications, and survival.


Results: Mean age was 61.7 ± 10.5 years; 65.3% were male; lung cancer was the primary site in 66.9%; solitary lesions accounted for 75%. Gross total resection was achieved in 68.9%; KPS improved from 68.6 to 76.4 after surgery; symptoms improved significantly; multimodal therapy was associated with better survival than surgery alone.


Conclusion: Intraoperative ultrasound is a practical and effective adjunct in brain metastasis surgery. It provides real-time imaging, helps detect residual tumor, compensates for brain shift-related limitations of neuronavigation, and is suitable for resource-conscious neurosurgical practice.

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References

1. Ng, P.R., et al., Surgical advances in the management of brain metastases. Neurooncol Adv, 2021. 3(Suppl 5): p. v4-v15.
2. de Lima Oliveira, M., et al., Ultrasonography During Surgery to Approach Cerebral Metastases: Effect on Karnofsky Index Scores and Tumor Volume. World Neurosurg, 2017. 103: p. 557-565.
3. Prada, F., et al., Multiparametric Intraoperative Ultrasound in Oncological Neurosurgery: A Pictorial Essay. Front Neurosci, 2022. 16: p. 881661.
4. Olah, L. and M. Olah, Potential benefits of intraoperative ultrasound in neurosurgery. J Clin Ultrasound, 2023. 51(4): p. 739-741.
5. Sirbu, O.M., et al., 2D Intraoperative Ultrasound in Brain Metastasis Resection: A Matched Cohort Analysis from a Single-Center Experience. Cancers (Basel), 2025. 17(14).
6. Policicchio, D., et al., Ultrasound-guided brain surgery: echographic visibility of different pathologies and surgical applications in neurosurgical routine. Acta Neurochir (Wien), 2018. 160(6): p. 1175-1185.
7. Caro-Osorio, E., L.A. Perez-Ruano, and J.A. Figueroa Sanchez, Concordance of Extent of Resection Between Intraoperative Ultrasound and Postoperative MRI in Brain and Spine Tumor Resection. Cureus, 2024. 16(11): p. e74101.
8. Erdogan, N., et al., Ultrasound guidance in intracranial tumor resection: correlation with postoperative magnetic resonance findings. Acta Radiol, 2005. 46(7): p. 743-9.
9. Dixon, L., et al., Intraoperative ultrasound in brain tumor surgery: A review and implementation guide. Neurosurg Rev, 2022. 45(4): p. 2503-2515.