KHẢO SÁT TÌNH HÌNH SỬ DỤNG THUỐC TRÊN NGƯỜI BỆNH HỘI CHỨNG VÀNH CẤP TẠI BỆNH VIỆN THỐNG NHẤT

Abstract

Background: Acute coronary syndrome is responsible for about 40% of deaths caused by cardiovascular diseases each year. Nowadays, there are many guidelines for the diagnosis and treatment of acute coronary syndrome. Objectives: To investigate the medication use of ACEIs or ARBs, beta-blockers, and statins in the first 24 hours of admission and in hospital discharge prescriptions in patients with acute coronary syndrome at Thong Nhat Hospital, Ho Chi Minh City. Method: A cross-sectional study was conducted on medical records of patients with hospital discharge diagnosis of non-ST elevation myocardial infarction, ST-elevation myocardial infarction or unstable angina at Thong Nhat Hospital from April 2020 to August 2020. Collected data for analysis included characteristics of patients with acute coronary syndrome, characteristics and rationality of ACEIs or ARBs, beta-blockers, and statins during the first 24 hours of admission and in hospital discharge prescriptions. Results: The median age of 174 patients was 64.5 (55–75), 71.3% was male. The majority of patients had comorbidities, of which hypertension was the most common one (94.8%). Within the first 24 hours of hospitalization, the proportions of patients who had an appropriate indication for ACEIs/ ARBs, beta-blockers, and statins were 62.6, 28.7 and 81.6%, respectively. The guideline adherence rates in hospital discharge prescriptions for ACEIs/ ARBs, beta-blockers, and statins were 84.5, 29.7 and 87.1%, respectively. Conclusion: The guideline adherence rate in patients with acute coronary syndromes after discharge was higher than in the first 24 hours of admission. Further adherence to treatment guidelines is required to optimize the treatment outcome in patients with acute coronary syndrome.