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Date Published: 15/04/2022
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DOI: https://doi.org/10.51298/vmj.v511i1.2056
Issue
Vol. 511 No. 1 (2022)
Section
Các bài báo
How to Cite
Tấn, Đỗ ., Thị Thu Thuỷ, P. ., & Thị Hồng Nhung, N. . (2022). IMPACTING FACTORS FOR OUTCOME OF FIXED-COMBINATION BRINMONIDIN AND BRINZOLAMID (SIMBRINZA) IN GLAUCOMA TREATMENT. Vietnam Medical Journal, 511(1). https://doi.org/10.51298/vmj.v511i1.2056

IMPACTING FACTORS FOR OUTCOME OF FIXED-COMBINATION BRINMONIDIN AND BRINZOLAMID (SIMBRINZA) IN GLAUCOMA TREATMENT

Đỗ Tấn1,, Phạm Thị Thu Thuỷ2, Nguyễn Thị Hồng Nhung1
1 Central Eye Hospital
2 Hanoi Medical University

Main Article Content

Abstract

Objectives: To evaluation some impacting factor for IOP lowering effect of fixed-combination Simbrinza in glaucoma treatment. Subjects and methodology: The prospective descriptive study. A total of 50 eyes of 30 glaucoma patients over 18 years old where target IOP has not been reached by one antiglaucoma medication. The patients were given a drop of Simbrinza and IOP was taken after 2 hours. If IOP reduction of at least 25% without side effect was achieved, then treatment was continued twice a day. The patients were followed up at 1 week, 1 month and 3 months. Results: There were some relating factors for IOP reduction capability of fixed-combination Simbrinza such as duration of disease, IOP, number of IOP lowering medications before treatment. Rate of IOP reduction of ≥ 40% was higher in duration of disease < 1 month group than duration of disease > 6-month group. Higher pre-treatment IOP group had higher rate of IOP reduction of ≥ 40%. There were no significant relation betwween age, gender, type glaucoma, disease stage, history and treatment outcome. Conclusion: The significant impacting factors for reduing intraocular pressure of fixed-combination Simbrinza in treatment glaucoma were duration of disease, pre treatment IOP, number of IOP lowering medications before treatment.

Article Details

Keywords

Simbrinza, glaucoma, IOP

References

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