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Date Published: 15/04/2022
Abstract Views: 97
Views PDF: 84
DOI: https://doi.org/10.51298/vmj.v511i1.2070
Issue
Vol. 511 No. 1 (2022)
Section
Các bài báo
How to Cite
Bảo Ngọc, L. ., Xuân Thanh, Đặng, Gia Hoàng Linh, L. ., Phương Thảo, M. ., & Đức Minh, Đỗ . (2022). THE ASSOCIATION BETWEEN ABCG2 V12M VARIANT AND SERUM URIC ACID LEVEL IN ADULTS. Vietnam Medical Journal, 511(1). https://doi.org/10.51298/vmj.v511i1.2070

THE ASSOCIATION BETWEEN ABCG2 V12M VARIANT AND SERUM URIC ACID LEVEL IN ADULTS

Lý Bảo Ngọc1, Đặng Xuân Thanh2, Lê Gia Hoàng Linh2, Mai Phương Thảo2, Đỗ Đức Minh2,
1 Pham Ngoc Thach University of Medicine, Ho Chi Minh City
2 University of Medicine and Pharmacy at Ho Chi Minh City

Main Article Content

Abstract

Background: Serum uric acid level is affected by genetic factor. The objective of this study was to identify the association between ABCG2 V12M variant and serum uric acid level in Vietnamese adults. Objectives and methods: In this case series study, ABCG2 V12M variant was genotyped in 150 participants using Sanger sequencing. Results: The frequency of ABCG2 V12M variant was 64,67% in Vietnamese adults. V12M was not significantly associated with serum uric acid level in the studied population by several analyzed models. V12M inclined to reduce serum uric acid level. Conclusion: The association between ABCG2 V12M variant and serum uric acid level is not observed in Vietnamese adults.

Article Details

Keywords

serum uric acid level, single nucleotide polymorphism, V12M, ABCG2 gene

References

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