EFFECTIVENESS OF ANTIMICROBIAL STEWARSHIP PROGRAM ON TREATMENT OF CHOLECYSTITIS AT A HOSPITAL IN HOCHIMINH CITY
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Abstract
Objective: To investigate pathogens and antibiotic use in the treatment of cholecystitis before and after applying for the antimicrobial stewardship program (ASP) at a hospital, Ho Chi Minh City. Methods: A before and after cross–sectional study was conducted on medical records of patients diagnosed with cholecystitis from 10/2018 to 3/2019 (before ASP) and from 10/2019 to 3/2020 (after ASP) at a hospital in Hochiminh City. Patient medical records were collected for data analysis including demographics, isolated organisms, antibiotic use, and treatment outcomes. The appropriateness of antibiotic use was assessed based on National antibiotic, SIS 2017, and Tokyo guidelines 2018. The effectiveness of ASP on treatment of cholecystitis was evaluated by comparing the rate of antibiotic appropriateness and treatment outcomes before and after applying ASP. Results: There were 104 medical records before ASP and 83 ones after ASP included in this study. The median age of patients was higher 60; 51-53% was man. E. coli (51.7%) and K. pneumoniae (27.6%) were the most common isolated organisms. The rate of appropriate antibiotic use in empiric treatment increased from 66.3% to 80.7% (p = 0,04). All patients recovered after treatment in both periods – before anf after ASP. Conclusion: The antimicrobial stewardship program increases the rate of appropriate antibiotic use.
Article Details
Keywords
antibiotic use, cholecystitis, antimicrobial stewardship program
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