TỔN THƯƠNG DA VẢY PHẤN DẠNG LICHEN VÀ ĐẬU MÙA CẤP TÍNH SAU TIÊM PHÒNG VẮC XIN BIONTECH/PFIZER: BÁO CÁO CA BỆNH

Abstract

Introduction: After nearly two years, there have been observational reports of skin reactions to COVID-19 vaccines so far. Cutaneous reactions after messenger RNA (mRNA) COVID-19 vaccines commonly includes early-onset local injection reactions, urticaria, and morbilliform eruptions. Pityriasis lichenoides et varioliformis acuta (PLEVA), one form of pityriasis lichenoides, is an uncommon cutaneous inflammatory disorder. This disease could appear after viral, bacterial infections and vaccinations. We describe a case of PLEVA following mRNA COVID-19 vaccine BioNTech/Pfizer at Dermatological clinic, National Children Hospital. Clinical case: A-13-year-old male patient with no history of systemic illness had multiple erythematous macules papules, some of which develop hemorrhagic or necrotic crusts at his back, chest and extremities after 2 weeks of  2nd BioNTech/Pfizer vaccination. Two days after emergence of cutaneous lesions, he was done biopsy with result: parapsoriasis, PLEVA. He was treated with high potency topical corticoid. Earlier lesions resolved and no new lesions appeared after 4 weeks.