CLINICAL PARACLINICAL ANTI-DRUG CHARACTERISTICS OF RECURRENT TUBERCULOSIS WERE TREATMENT AT PHAM NGOC THACH HOSPITAL, HO CHI MINH CITY
Main Article Content
Abstract
Purpose: Evaluation for clinical symptoms and Xray findings of recurrent tuberculosis. Objective and method: 56 patients, 39 males and 17 females (male/female=2.3). Male is common in range 18-70 years old, female is common in 18-40 years old. A prospective, cross-sectional study of 56 recurrent tuberculosis patients were diagnostic and treatment at Pham Ngoc Thach Hospital, Ho Chi Minh City in 2 months. Analysis of algorithm data base on statistical software and give results to research objectives. Results: The most common of systemic symptoms was fever, accounting 57,14%. Common functional symptoms was long–term coughs, 71,43%. The physical symptoms were poor, the most common one was bubling sound, accounting for 30.9%. Chest – xray: Lesion in right lung (46,43%) was more than lesion in left lung (32,14%). Homogeneous infiltration was most common lesions (64,28%). Sputum AFB test: positive in 58,93% and negative in 41,07 %. Resistance INH Tuberculosis in 12 patients, accounting 21,42%. Resistance RMP = INH Tuberculosis in 5 patients, accounting 8,93%. Non – resistance TB was in 39 patients, accouting 69,64%. Conclusion: Drug - Resistance TB or recurrent TB is always a topical issue. Diagnostic and treatment is more difficulty and highly complex than new TB. Clinical and para – clinical research is need for the scientific community and practical application.
Article Details
Keywords
Tuberculosis, drug - resistance tuberculosis, recurrent tuberculosis
References
2. Joo Hee Lee, M.D., Kyung-Wook Jo, M.D, Ph.D., and Tae Sun Shim, M.D, Ph.D (2018) Correlation between GenoType MTBDRplus Assay and Phenotypic Susceptibility Test for Prothionamide in Patients with Genotypic Isoniazid Resistance.www.e-trd.org, Tuberc Respir Dis, Published online.
3. Jamshid Gadoev, Damin Asadov, Anthony D. HarriesRecurrent tuberculosis and associated factors: A five - year countrywide study in Uzbekistan (2017), “”, PLoS One. 2017; 12(5): e0176473. 10.1371/journal.pone.0176473
4. Korhonen V, Soini H, Vasankari T(2017), “Recurrent tuberculosis in Finland 1995-2013: a clinical and epidemiological cohort study”, BMC Infect Dis. 2017 Nov 16;17(1):721. doi: 10.1186/s12879-017-2818.
5. Nguyễn Thị Phương Thảo (2008), “Nghiên cứu đặc điểm lâm sàng, cận lâm sàng, tính kháng thuốc của vi khuẩn lao trong lao phổi tái phát”. Luận văn Thạc sỹ, Học viện Quân y, Hà Nội 70tr.
6. Nguyễn Thị Hậu (2015), “Nghiên cứu lâm sàng, cận lâm sàng, tỷ lệ kháng thuốc và kết quả điều trị tấn công ở bệnh nhân lao phổi tái phát”. Luận văn Thạc sỹ, Học viện Quân y, Hà Nội 67tr.
7. Jacobs MG, Pinto Junior VL(2020), “Characterization of drug-resistanttuberculosis in Brazil, 2014”, Epidemiol Serv Saude. 2020 Feb 3;28(3):e2018294. doi: 10.5123/S1679.