MỐI TƯƠNG QUAN GIỮA ĐẶC ĐIỂM KHÁNG THUỐC LÂM SÀNG, CẬN LÂM SÀNG CỦA BỆNH NHÂN LAO PHỔI TÁI PHÁT SAU 2 THÁNG ĐIỀU TRỊ

Abstract

Purpose: Research on the correlation between clinical, para – clinical with resistant characteristic  in recurrent TB patients.  Objective and method: A prospective, cross-sectional study of 56 recurrent tuberculosis patients were diagnostic and treatment at Pham Ngoc Thach Hospital, Ho Chi Minh City in 2 months. Analysis of algorithm data base on statistical software and give results to research objectives. Results: Fever, cough and breathing difficulties symptoms were common in single drug– resistant TB patient. Chest X ray findings:Mild level lesion in multi – resistant TB(approximate 50%) was more commonly than single – resistant TB (approximate 25%). Moderate and severe lesion were only in the single – resistant TB. TB cavity was in all multi – resistant TB patient and about 25% in single – resistant TB patient. The correlation between positive AFP sputum smears results and resistant characteristic: Pulmonary TB patients with AFB smear-positive (1+) include 7 patients with INH resistance and 3 patients with RMP + INH resistance. Pulmonary TB patients with AFB smear-positive (2+) include 3 patients with INH resistance and 1 patient with RMP + INH resistance. Pulmonary TB patients with AFB smear-positive (3+) include 2 patients with INH resistance and 1 patient with RMP + INH resistance. Pulmonary TB patients with AFB smear-positive levels was not correlation in patients with INH resistance or patient with RMP + INH resistance. Conclusion: The clinical and paraclinical of resistant TB is different from the new TB. Research on the correlation between clinical and para – clinical of  drug - resistance of TB is always treat and prevent significance.