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Date Published: 27/04/2022
Abstract Views: 222
Views PDF: 158
DOI: https://doi.org/10.51298/vmj.v513i1.2340
Issue
Vol. 513 No. 1 (2022)
Section
Các bài báo
How to Cite
Ngọc Linh, P. ., & Ngọc Hà, N. . (2022). CLINICAL AND SUBCLINICAL CHARACTERISTICS OF BETA THALASSEMIA PATIENTS WITH REDUCE EF% ON DOPPLER ECHOCARDIOGRAPHY IN THAI NGUYEN CENTRAL HOSPITAL. Vietnam Medical Journal, 513(1). https://doi.org/10.51298/vmj.v513i1.2340

CLINICAL AND SUBCLINICAL CHARACTERISTICS OF BETA THALASSEMIA PATIENTS WITH REDUCE EF% ON DOPPLER ECHOCARDIOGRAPHY IN THAI NGUYEN CENTRAL HOSPITAL

Phạm Ngọc Linh1, Nguyễn Ngọc Hà1,
1 Thai Nguyen University of Medicine and Pharmacy

Main Article Content

Abstract

The aims were to describe the clinical and subclinical characteristics of beta thalassemia patients with reduce EF% on Doppler echocardiography in Thai Nguyen Central Hospital. Methods: A cross-sectional study was performed on 67 patients with thalassemia treated at the Clinical Hematology Department, Thai Nguyen Central Hospital from 1/2021 to 1/2022. Results: The female rate was higher than male rate; the majority of patients are ethnic minorities (71.6%); the age group <15 accounted for the highest percentage (50.7%), the mean age of diagnosis of the disease group was 2(±2) lower than the control group. Common clinical symptoms were: dizziness (41%) and fatigue (40%). The test showed that: mean Hb, mean Bil TT & TP, mean SGOT of the the disease group with reduced left ventricular ejection fraction lower than the control group; the ultrasound index of the disease group was also lower than the control group. There was a statistically significant difference in the mean age of diagnosis, the frequency of blood transfusions ≥5 times/year in the group of thalassemia patients with reduced left ventricular ejection fraction with the control group (p<0.05); Mean EF (53.16±1.12), mean FS (31.16±2.46) evaluating left ventricular systolic function of the disease group were lower than the control group, with p<0.05; There was a statistically significant difference between the disease group with blood ferritin ≥ 2500 ng/ml of the patient group and the control group, with p< 0.05.

Article Details

Keywords

Thalasamie, Thai Nguyen Central Hospital

References

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