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Date Published: 27/04/2022
Abstract Views: 643
Views PDF: 308
DOI: https://doi.org/10.51298/vmj.v513i1.2375
Issue
Vol. 513 No. 1 (2022)
Section
Các bài báo
How to Cite
Trường Sinh, C. ., & Ngọc Quý, N. . (2022). DETERMINATION OF CONCENTRATION, RELATIONSHIP, CORRORATION BETWEEN PLASMA NT-pro BNP CONCENTRATION WITH LEVEL, MORPHOLOGY AND FUNCTION OF LEFT VENTRICUALR IN HEART FAILURE PATIENTS AT VINH CITY UNIVERSITY HOSPITAL. Vietnam Medical Journal, 513(1). https://doi.org/10.51298/vmj.v513i1.2375

DETERMINATION OF CONCENTRATION, RELATIONSHIP, CORRORATION BETWEEN PLASMA NT-pro BNP CONCENTRATION WITH LEVEL, MORPHOLOGY AND FUNCTION OF LEFT VENTRICUALR IN HEART FAILURE PATIENTS AT VINH CITY UNIVERSITY HOSPITAL

Cao Trường Sinh1,, Nguyễn Ngọc Quý1
1 Vinh Medical University

Main Article Content

Abstract

Aim: To determine the relationship and correlation between plasma NT-proBNP concetration with the degree and stage of heart failure and left ventricular morphology and function. Subjects and methods: 109 patients were diagnosed the heart failure according to ESC 2016 criteria with the average age of 76.17 ± 12.18. Clinical examination, echocardiography and NT-proBNP test were performed to assess the correlation between plasma NT-proBNP levels and the degree and stage of heart failure and left ventricular morphology and function. Resulls: The mean NT-proBNP concentration in heart failure patients was 6839.06 ± 644.51pg/ml. The concentration of NT-proBNP is related to the degree of heart failure according to the classification of NYHA, ACC/AHA with the difference between levels of heart failure with statistical significance p<0.001. The concentration of NT-proBNP and the left ventricular morphological indices (LVDd, LVM, LVMI) were positively correlated with the correlation coefficient r = 0.772, r = 0.793, r = 0.722; p<0.001, respectively. NT-proBNP concentration and left ventricular ejection fraction were negatively correlated with the correlation ratio r = -0.748, p < 0.001. Conclusion: NT-proBNP concentration is related to NYHA, ACC/AHA classification of heart failure, there is a positive correlation between NT-proBNP concentration and left ventricular morphology and negative correlation with left ventricular function.

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