EFFECT OF ENDOSCOPIC SUBMUCOSAL DISSESION ON TREAMENT HI-GRADE DYSPLASIA AND EARLY GASTRIC CANCER

Nguyễn Thế Phương1,, Nguyễn Công Long2, Vũ Trường Khanh3, Đào Trần Tiến3, Trịnh Tuấn Dũng3, Đào Văn Long1
1 Hanoi Medical University
2 Department of Gastroenterology and Hepatology, Bach Mai Hospital
3 Tâm Anh Hospital

Main Article Content

Abstract

Early gastric cancer (EGC), hi-grade dysplasia (HGD) are defined gastric superficial lesions that invade no more deeply than the submucosal layer. Endoscopic submucosal dissection (ESD) is a well-established and minimally invasive treatment for premalignant and early malignant gastrointestinal (GI) lesions. There are lack of study on ESD procedure in Vietnam. A prospective cross-sectional study aimed to evaluation of efftiveness of ESD procedure in treamet EGC and HGD in Vietnam. 77 patients with EGC or  HGD were peformed ESD, showed that the rate of curative treament was 98,7% the average time of ESD procedure was 86.7 mins; factors related to the longer procedure time were location (antrum vs body of the stomach, 76.7 vs 112,4 mins, respectively, p=0.05), the size of the tumor (<30 mm vs  30-50mm, 67.3 vs 115.7 mins, respectively, p<0.05); bleeding during procedure time was common complication, 32,5%); perforationwas had 1 case but no need surgery. ESD is an effective and safe therapy in the management of early gastric neoplasms.

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References

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