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Date Published: 17/07/2022
Abstract Views: 419
Views PDF: 234
DOI: https://doi.org/10.51298/vmj.v516i1.2947
Issue
Vol. 516 No. 1 (2022)
Section
Các bài báo
How to Cite
Tuấn Đạt, N. ., Văn Chi, N. ., Trần Hưng, H. ., Ngọc Sơn, Đỗ ., Hữu Quân, N. ., Anh Tuấn, N. ., & Quốc Chính, L. . (2022). ASSESSMENT OF THE TREATMENT RESULTS AND BRAIN PROTECTION EFFECTS OF THE 33°C TARGETED HYPOTHERMIA TREATMENT IN THE TREATMENT OF COMA PATIENTS AFTER CARDIAC ARREST. Vietnam Medical Journal, 516(1). https://doi.org/10.51298/vmj.v516i1.2947

ASSESSMENT OF THE TREATMENT RESULTS AND BRAIN PROTECTION EFFECTS OF THE 33°C TARGETED HYPOTHERMIA TREATMENT IN THE TREATMENT OF COMA PATIENTS AFTER CARDIAC ARREST

Nguyễn Tuấn Đạt1,, Nguyễn Văn Chi1, Hà Trần Hưng2, Đỗ Ngọc Sơn1, Nguyễn Hữu Quân1, Nguyễn Anh Tuấn2, Lương Quốc Chính1
1 Bach Mai Hospital
2 Hanoi Medical University

Main Article Content

Abstract

Purposes: To evaluate the therapeutic and brain-protective effects of the 33°C targetted hypothermia method in the treatment of comatose patients after out-of-hospital cardiac arrest. Subjects and methods: A controlled intervention study on 136 comatose patients after out-of-hospital cardiac arrest who were successfully resuscitated with return of spontaneous circulation, 68 patients received 33°C target hypothermia, 68 patients Retrospective control group routine treatment at A9 emergency department, Bach Mai Hospital from January 2013 to January 2020. Results: Survival was higher in the 33°C target hypothermia group than in the control group at discharge (58.8% vs 33.8%; p= 0.003) as well as at 6 months (51.5% vs 10.3%; p < 0.001). The good neurological outcome was higher in the hypothermic group than in the control group at 30 days (36.7% vs 10.3%; p < 0.001) as well as at 6 months (39.7% vs. 3%; p<0.001). Conclusions: Targeted hypothermia treatment of 33°C improves survival as well as good neurological outcomes for comatose patients after out-of-hospital cardiac arrest.

Article Details

Keywords

Cardiac arrest, Sudden cardiac death, Cardiopulmonary resuscitation, Therapeutic hypothermia, The Cerebral Performance Category (CPC) score

References

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