ĐÁNH GIÁ MỘT SỐ ĐẶC ĐIỂM LÂM SÀNG, CỘNG HƯỞNG TỪ VÀ MỐI LIÊN QUAN ĐẾN MỨC ĐỘ TÀN TẬT CỦA BỆNH NHÂN XƠ CỨNG RẢI RÁC

Abstract

Objective: To describe some clinical features, magnetic resonance image (MRI), and the relationship with the level of disability in patients with multiple sclerosis (MS). Subjects and methods: We studied 71 patients with MS based on McDonald's 2017 criteria. A cross-sectional study was evaluated after the treatment course according to the Expanded Disability Status Scale (EDSS). Results: The majority of patients were under 50 years old (75%). Mean age of onset 37±13. Females are more common than males, female/male ratio ≈ 3,2:1 (p<0.05). The onset of visual damage on one side was 80% (p<0.05). The clinical symptoms are the main symptoms of spinal cord lesions: motor paralysis (73.3%), sensory disturbance (83.1%), sphincter disturbance (45.1%), spasticity (36,6%), brain damage symptoms are less common. Magnetic resonance image: spinal cord injury 73.2%, brain 35.2%, of which ≥3 paraventricular lesions 19.7%. Factors related to EDSS: numbness of limbs, motor paralysis, sphincter disturbance, spasticity, a combination of symptoms; MRI with spinal cord injury and at least 3 paraventricular lesions. Conclusions: The patients with MS are mainly young, mostly female, spinal lesions cause them disabled.