KHẢO SÁT NỒNG ĐỘ D-DIMER Ở BỆNH NHÂN CAO TUỔI NẰM VIỆN CÓ NGUY CƠ HUYẾT KHỐI TĨNH MẠCH SÂU

Abstract

Background: Deep vein thrombosis (DVT) is the leading cause of death in elderly patients (DEPs) for inpatient treatment. Early diagnosis and treatment of DVT increases survival rates. In particular, D-dimer levels have a high sensitivity of 94-96% in most patients with DVT. DVT is rare in under-40s but more common in people over the age of 60. Objective: Identifying the average D-dimer concentration and the association between D-dimer levels, doppler ultrasound in DVT diagnostic DEPs with pathological characteristics at Ho Chi Minh City Thong Nhat hospital. Methods: Cross-sectional study from January to May 2022 on 260 DEPs hospitalizations for inpatient treatment at risk of DVT (with Wells score ≥ 1 point) at Ho Chi Minh City Thong Nhat hospital. Results: D-dimer levels of patients with DVT were median at 3106.5 ng/ml and about 1.5 times higher than those without DVT; with positive doppler ultrasounds of 36 out of 260 patients (or 13.85%).  There was an association between D-dimer levels and age groups, cardiovascular disease and trauma (p<0.05). Conclusion: The patient has a Wells score of ≥ 1 point; D-dimer levels (>500ng/ml) with positive doppler ultrasound have a DVT predictive value. Age and accompanying pathologies are factors affecting DVT in DEPs hospitalization for inpatient treatment.