CLINICAL, PARACLINICAL CHARACTERISTICS AND TREATMENT RESULTS OF CHILDREN WITH ANAPHYLAXIS AT HAI PHONG CHILDREN'S HOSPITAL IN 2019 – 2020

Đinh Văn Thức1,2, Phạm Văn Thức1, Nguyễn Mai Phương1,2, Đinh Dương Tùng Anh1,2,
1 Haiphong University of Medicine and Pharmacy
2 Haiphong Children's Hospital

Main Article Content

Abstract

Anaphylaxis is a particularly serious allergic condition that can be life-threatening if not diagnosed and treated promptly. Objectifs: To describe the clinical and subclinical characteristics of children with anaphylaxis at Hai Phong Children's Hospital in the years 2019-2020 and comment on the treatment results in the above patients. Materials and methods: Descriptive study using retrospective data of 54 cases of children with anaphylaxis selected by convenience sampling method. Results: The main symptoms of anaphylaxis were: cardiovascular, neurological and skin symptoms. Respiratory and gastrointestinal symptoms were seen at a lower rate. The rate of children with acidemia in shock was 50% and increased lactate was 75.9%. 100% of children received the first dose of intramuscular adrenaline. Solumedrol, dimedrol were the drugs most commonly used concurrently with adrenaline. The rate of children re-shocked was low (1.9%). Most of the patients were symptom-free (87.0%), 13.0% of the children got worse or did not improve, requiring referral. Conclusion: Early detection and treatment of anaphylaxis are decisive and prognostic factors. The main treatment is intramuscular adrenaline injection as soon as possible, and prevent re-exposure to the allergen causing anaphylaxis. It is necessary to strictly manage the use of drugs, limit intravenous routes, preferably oral or intramuscular use.

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References

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