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Date Published: 09/10/2022
Abstract Views: 248
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DOI: https://doi.org/10.51298/vmj.v518i2.3416
Issue
Vol. 518 No. 2 (2022)
Section
Các bài báo
How to Cite
Minh Ngọc, V. ., Văn Quân, L. ., Thị Mai Ly, N. ., Văn Trân, P. ., Phú Cầu, Đồng ., & Việt Hùng, Đinh . (2022). COFFEE BEAN EXTRACT ON PREVENTING FROM THE OBESITY AND HYPERLIPIDEMIA IN RATS. Vietnam Medical Journal, 518(2). https://doi.org/10.51298/vmj.v518i2.3416

COFFEE BEAN EXTRACT ON PREVENTING FROM THE OBESITY AND HYPERLIPIDEMIA IN RATS

Vũ Minh Ngọc1, Lê Văn Quân2,, Nguyễn Thị Mai Ly2, Phạm Văn Trân2, Đồng Phú Cầu2, Đinh Việt Hùng2
1 Institute 69, The President Ho Chi Minh's Mausoleum Protecting Command
2 Military Hospital 103

Main Article Content

Abstract

Objective: To investigate effects of the green coffee bean extract (GCBE) on preventing from the obesity and hyperlipidemia in rats. Methods: 60 rats were feed by high-fat food and treated by saline, simvastatin 2mg/kg or GCBE at doses 200mg/kg, 300mg/kg and 400mg/kg in 8 continuous days. Changes in body weights, body mass index (BMI), serum concentrations of triglyceride and cholesterol were measured. Results: GCBE at dose 400mg/kg induced decreases in body weights and BMI of rats from the 6th to the 8th weeks (p<0,05). In group of rats treated GCBE at doses 300mg/kg and 400mg/kg, there were decreased in serum concentrations of triglyceride from the 4th to the 8th weeks in compared to the control group (p<0,05). However, a significant differences in serum concentrations of cholesterol between groups were not found (p<0,05). Conclusion: GCBE at doses 300mg/kg and 400mg/kg have good effects on preventing from obesity and hypertriglyceridemia in rats.

Article Details

Keywords

Obesity, GCBE, rats

References

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