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Date Published: 09/10/2022
Abstract Views: 434
Views PDF: 223
DOI: https://doi.org/10.51298/vmj.v518i2.3418
Issue
Vol. 518 No. 2 (2022)
Section
Các bài báo
How to Cite
Thị Minh Hằng, L. ., Hoàng Anh(B), N. ., Trần Nam Tiến, N. ., Thanh Hiền, N. ., Đình Hòa, V. ., Hoàng Anh, N. ., & Quang Thùy, L. . (2022). PHÂN TÍCH ĐẶC ĐIỂM SỬ DỤNG VANCOMYCIN TRÊN BỆNH NHÂN NẶNG ĐIỀU TRỊ HỒI SỨC TÍCH CỰC TẠI BỆNH VIỆN HỮU NGHỊ VIỆT ĐỨC. Vietnam Medical Journal, 518(2). https://doi.org/10.51298/vmj.v518i2.3418

PHÂN TÍCH ĐẶC ĐIỂM SỬ DỤNG VANCOMYCIN TRÊN BỆNH NHÂN NẶNG ĐIỀU TRỊ HỒI SỨC TÍCH CỰC TẠI BỆNH VIỆN HỮU NGHỊ VIỆT ĐỨC

Lê Thị Minh Hằng1, Nguyễn Hoàng Anh(B)2, Nguyễn Trần Nam Tiến2, Nguyễn Thanh Hiền1, Vũ Đình Hòa2, Nguyễn Hoàng Anh2, Lưu Quang Thùy1
1 Vietduc University Hospital
2 The National Centre of Drug Information and Adverse Drug Reactions Monitoring (National DI & ADR Centre), Hanoi University of Pharmacy

Main Article Content

Abstract

Objective: To analyze the characteristics of vancomycin using in adult patients at the Intensive Care Unit 2, Anesthesia & Surgical Intensive Care Center, Viet Duc Hospital. Subjects and methods: A retrospective descriptive study based on data collected from medical records of adult patients hospitalized at the ICU 2 from January to September 2021. Results: Vancomycin is mainly indicated for empiric treatment for common infections in surgical patients, only 18.4% of the samples were isolated from Gram (+). 31% of patients in this study received a relatively high mean loading dose (40 mg/kg). The initial maintenance dose was mainly 1g every 12 hours, 1g every 8 hours and only 2 cases needed 1g every 6 hours. 11.96% of patients reported kidney complications. Conclusion:  It is necessary to develop a protocol of the vancomycin using as well as vancomycin therapeutic drug monitoring (TDM) according to the update guidelines in the world to optimize the dose regimen, to ensure the effectiveness and limit the toxicity of this drug.

Article Details

Keywords

Vancomycin, Intensive care unit, Viet Duc Hospital, surgery, analysis of drug using

References

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