PREDICTORS OF SYMPTOMATIC INTRACRANIAL HEMORRHAGE AFTER MECHANICAL THROMBECTOMY AT NGHE AN FRIENDSHIP GENERAL HOSPITAL

Võ Thế Nhân1,, Nguyễn Ngọc Hoà1
1 Nghe An Friendship General Hospital

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Abstract

Background and purpose. Symptomatic intracranial hemorrhage (sICH), associated with poor outcome, is a potentially serious complication of mechanical thrombectomy (MT) for acute ischemic stroke patients. This study aimed to identify predictive factors of sICH post MT at Nghệ An Friendship General Hospital. Methods. This case-control study enrolled 230 acute ischemic stroke patients with large vessel occlusion undergoing MT. Participants were divided into two groups: sICH group (n=31) and control group (n=199). sICH was diagnosed according to the Heidelberg Bleeding Classification. Univariate analysis and multivariate logistic regression were used to determine the predictors of sICH. Results. After multivariate analysis, baseline platelet count <180 × 109/L (OR 5,48, 95%CI 1,69-19,50), admission ASPECTS (OR per 1-point increase 0,37, 95%CI
0,20-0,63), poor collateral circulation (OR 8,04, 95%CI 2,54-28,3) and groin-to-recanalization time >60 minutes (OR 5,43, 95%CI 1,55-22,5) were found to be independent predictive factors of sICH. Conclusions. Several predictive factors of sICH post MT were identified. This knowledge plays an important role in benefit - risk counseling, selection of treatment strategies, improvement of patient monitoring protocol, enhancement of the therapeutic outcome and prognosis of MT.

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References

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