THE CURRENT STATE OF BLOOD GLUCOSE CONTROL AND SOME RELEVANT FACTORS IN PATIENTS WITH TYPE 2 DIABETES MELLITUS WITH AFB-POSITIVE NEW PULMONARY TUBERCULOSIS

Vũ Thị Bích Ngọc1,, Nguyễn Khoa Diệu Vân2
1 National Hospital 74
2 Hanoi Medical University

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Abstract

Objectives: The study aims to investigate the status of glycemic control in patients with type 2 diabetes mellitus with new AFB (+) pulmonary tuberculosis at National 74 Hospital, to review the results of pulmonary tuberculosis treatment and some factors related to the study subjects. Subjects and methods: A retrospective and prospective description of 115 patients with type 2 diabetes mellitus with new pulmonary TB AFB (+) at National 74 Hospital from January 1, 2020 to August 15, 2022. Results: Male/female ratio: 87.8% and 12.2%; average age 58.5 ±12.3 (Min 38, Max 89), group over 50 years old (76.6%); sick from 1 year to 5 years (39.1%), ≥ 10 years (7%); mean BMI 20.17 ± 3.01 (Min 13.3 Max 29.48), mean HbA1c 8.70 ± 2.8 (Min 4.63, Max 16.8), HbA1c reached the target accounted for 49.6%; Patients controlled 3 factors HbA1c, HA, LDL-C (11.2%); Diabetic diet, treatment adherence, exercise and patient's weight are related to blood glucose control (p < 0.05); cure rate of pulmonary tuberculosis (87.8%), failure rate (12.2%); symptoms of cough, sputum production and chest tightness after 4 months of blood glucose control group achieved reduction compared to blood glucose control group failed, (p < 0.001); The group with good blood glucose control had a good cure rate, the rate of change of lesions on X-ray was good after 2 months, the rate of sputum negative was higher than the group with poor blood glucose control, the difference was statistically significant with p < 0.05. Conclusion: Control of HbA1c reached the target of 49.6%, control achieved 3 factors of HbA1c, HA, and LDL-C (11.2%). Taking medication regularly, eating a diabetic diet, exercising daily and maintaining a normal weight help control blood glucose better. The group with good blood glucose control had a good cure rate, the rate of change of lesions on X-ray was good after 2 months, the rate of sputum negative was higher than the group with poor blood glucose control.

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References

1. Bộ Y tế (2020), Hướng dẫn chẩn đoán và điều trị ĐTĐ týp 2 năm 2020, Quyết định 5481/QĐ-BYT.
2. Bộ Y tế - CTCLQG (2020), Hướng dẫn chẩn đoán, điều trị và dự phòng bệnh lao năm 2020, Quyết định 1314/QĐ-BYT .
3. Đã đến lúc Chấm dứt Bệnh Lao tại Việt Nam! Accessed September 25, 2021. https://www.who.int/vietnam/vi/news/commentaries/detail/it-s-time-to-end-tb-in-viet-nam
4. Đặng Văn Khoa, Hà Văn Sen (2018). Đặc điểm lâm sàng, cận lâm sàng và kết quả điều trị lao phổi mới AFB (+) có đái tháo đường bằng phác đồ 2(E)SHRZ/4RHE tại Bệnh viện 74 Trung ương. Tạp chí Y học Việt Nam, tập 462, số 2, tháng 1/2018.
5. Phan Thanh Dũng và Cộng Sự (2012), Đặc Điểm Lao Phổi ở Bệnh Nhân Đái Tháo Đường. Kỷ Yếu HNKH Bệnh Viện An Giang.”
6. Trần Thị Lịch, Nguyễn Khoa Diệu Vân (2019). Thực trạng kiểm soát đường huyết và các yếu tố nguy cơ ở bệnh nhân đái tháo đường týp 2 điều trị ngoại trú. Tạp chí Y học Việt Nam, tập 481, số 2 tháng 8/2019.
7. https://suckhoedoisong.vn/nguy-hiem-khi-benh-nhan-dai-thao-duong-mac-lao-phoi-169170089.htm
8. Huangfu P, Pearson F, Ugarte-Gil C, Critchley J. Diabetes and poor tuberculosis treatment outcomes: issues and implications in data interpretation and analysis. Int J Tuberc Lung Dis. 2017;21(12):1214-1219. doi:10.5588/ijtld.17.0211.