TỔNG QUAN HỆ THỐNG HIỆU QUẢ MỘT SỐ PHƯƠNG PHÁP ĐIỀU TRỊ NANG RĂNG SỪNG HÓA

Abstract

Objectives: To evaluate the effectiveness of odontogenic keratocyst (OKCs) surgery by peripheral osteotomy and chemical curettage with Carnoy’s solution according to systematic review method. Materials and methods: Systematic review and meta-analysis of postoperative recurrence rate data of peripheral osteotomy and chemical curettage with Carnoy’s solution from articles, theses on Pubmed database, EBSCOhost Research Databases, ScienceDirect, Hanoi Medical University library in English and Vietnamese formats. Results: The study was taken from 3 main databases (Pubmed, Science direct, Cochrane..) with a total of 331 studies (Pubmed: 191, Science direct: 129, Cochrane: 9, other texts: 2), after removing duplicate studies (13 studies), we screened 321 studies. Conducted title and abstract to eliminate 276 inappropriate studies. 45 studies were reviewed in full text based on inclusion criteria. A total of 25 nonconforming studies were excluded, including 9 reviews, 4 including unsegregated NBCCS cases, 6 studies with insufficient follow-up time, 3 studies with case numbers less than 10, one study did not know the recurrence rate and 2 studies did not use the selected method. Twenty qualified studies were included for meta-analysis with 591 keratolytic cystic lesions (PO: 122, CS: 511). The results of the meta-analysis showed that the recurrence rate after treatment of peripheral osteotomy in the meta-analysis of 8 studies was 20% (95% CI: 10-31), of chemical curettage with Carnoy’s solution after treatment of odontogenic keratocyst was 6% (95% CI: 1.0-12.0).