ĐÁNH GIÁ TÁC DỤNG CHỐNG VIÊM CẤP CỦA BÀI THUỐC QUYÊN TÝ THANG GIA GIẢM TRÊN MÔ HÌNH GÂY PHÙ CHÂN CHUỘT BẰNG CARRAGEENIN

Abstract

Background: “Quyen Ty Thang increase or decrease” (QTTGG) is an experimental remedy based on the traditional medicine “Quyen Ty Thang” has been used and evaluated to have a good analgesic effect on patients with osteoarthritis pain who come for examination and treatment at Kien Giang hospital of Traditional Medicine and Pharmacy. The present study is going to clarify the mechanism of pain relief through acute anti-inflammatory effects of the drug on experimental animals, creating a basis for clinicians in treatment. Objective: Access the acute anti-inflammatory effect of QTTGG remedy in the carrageenan-induced rat paw edema model. Materials and methods: The acute anti-inflammatory effect was evaluated in the rat paw edema model with Carrageenin, according to the method of Winter et al. Results: QTTGG at a dose of 23.6g/kg/day has been shown acute anti-inflammatory activity as good as Diclofenac, a substance with proven anti-inflammatory effects, at a dose of 15mg/kg/day. Conclusions: QTTGG has been demonstrated to have good anti-inflammatory effects on the carragenin-induced white sewer rat paw edema model.