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OVERVIEW OF DIAGNOSIS OF GROUP A STREPTOCOCCAL PHARYNGITIS
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Abstract
Objectives: Analysis of diagnosis of group A streptococcal pharyngitis. Study Design: Scoping review. Methods: We searched the database on PubMed, Medline, the electronic library of Hanoi Medical University from 2010 to 2022 related to diagnosis of group A streptococcal pharyngitis. Results: 40 studies were included in this review. According to US and French guidelines, microbiological tests are necessary to diagnose acute streptococcal pharyngitis. Sensitivity decreased and specificity increased in groups of patients with increasing Centor scores. 50% of the studies showed similarity between RADT and throat cultures with ratio of >90%. The sensitivity of RADT mainly ranges from 80-95% and the specificity is high at approximately 95%. Conclusions: Centor and McIsaac scoring systems can assist clinicians in making a diagnosis of group A streptococcal pharyngitis according to some guidelines. Besides throat culture as the gold standard for definitive diagnosis, RADT with its advantages: high sensitivity, high specificity, low cost, ease of implementation and rapid results is also an important method in diagnosis.
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Keywords
pharyngitis, sore throat, tonsillitis, pharyngotonsillitis, Streptococcus pyogenes, Group A-haemolytic Streptococcus pyogenes, streptococcal pharyngitis
References
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