KHẢO SÁT MỘT SỐ TRIỆU CHỨNG NGOÀI THỰC QUẢN Ở BỆNH NHÂN TRÀO NGƯỢC DẠ DÀY – THỰC QUẢN

Abstract

Objectives: To describe some features of extraesophageal symptoms in patients with gastroesophageal reflux disease. Methods: A cross-sectional study was conducted in patients over 18 years old with gastroesophageal reflux disease with extraesophageal symptoms who came to the outpatient clinic and underwent upper gastrointestinal endoscopy at the Gastroenterology - Hepatobiliary Center Bach Mai Hospital from 8/2021 to 6/2022. Gastroesophageal reflux disease was diagnosed based on a GERDQ score ≥ 8 and/or a lesion of reflux esophagitis on endoscopy according to the Los Angeles classification. Extraesophageal symptoms were diagnosed when at least one of the symptoms was chest pain, chronic cough, wheezing, hoarseness, and throat obstruction and other causes were excluded. Results: We recorded 212 patients who were eligible for the study. The three most common extra-esophageal symptoms were cough, sore throat and chest pain with 49,1%, 46,7% and 45,3%, respectively. Two symptoms of hoarseness and wheezing were rarer with the rate of 9,9% and 9,4%, respectively. The proportion of patients with gastroesophageal reflux disease who had reflux esophagitis was 36,3%, levels of Los Angeles A, B, C, D were 87%, 10,4%, 1,3% and 1,3%. The rate of throat obstruction in the group of gastroesophageal reflux disease without esophageal lesions was statistically significantly higher than in the group of gastroesophageal reflux disease with esophagitis. Conclusion: The most common extraesophageal symptoms were dry cough, sore throat and chest pain, two rarer symptoms of hoarseness and wheezing. The rate of throat obstruction in the group with gastroesophageal reflux disease without esophagitis was higher than in the group with esophagitis