KẾT QUẢ BƯỚC ĐẦU ĐIỀU TRỊ U TẾ BÀO THẦN KINH ĐỆM BẬC CAO TẠI BỆNH VIỆN K TRUNG ƯƠNG

Abstract

Objectives: To initially evaluate the results of treatment for high-grade glioma. Subjects and methods: A descriptive, prospective study on 52 high-grade glioma patients with indications for surgery, chemotherapy and radiotherapy at K Hospital, Tan Trieu campus, from January 1, 2019 to December 12. 2020. Results: Patients were predominantly male (61.5%) with a mean age of 45.2 years. Most patients had surgery to remove the maximum possible tumor (remove all and most of the tumor), accounting for 96.2%. Six months after surgery, the most commonly reported clinical symptoms were headache (55.8%), hemiplegia (21.2%), epileptic seizures (15.4%), sadness vomiting and vomiting (9.6%); blurred vision, reduced visual acuity (11.5%), the mean Karnofsky score is 67.7; assessment of objective response according to RECIST, 51 out of 52 patients achieved disease control rate (98.1%). Conclusion: Patients with high-grade glioma treated with surgery combined with chemotherapy and radiation gave relatively good results.  after 1 and 6 months after surgery, patients had a high rate of disease control in terms of objective response according to RECIST.