ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG VÀ KẾT QUẢ ĐIỀU TRỊ BỆNH NHÂN NHIỄM ĐỘC MỘT SỐ KIM LOẠI TẠI TRUNG TÂM CHỐNG ĐỘC BỆNH VIỆN BẠCH MAI

Abstract

Objectives: to describe the epidemiology, clinical, subclinical characteristics and treatment outcomes of metal poisoned patients at the Poison Control Center of Bach Mai Hospital. Subjects and methods: A descriptive study on 60 patients with metal poisoning (tin, copper, lead, arsenic, mercury) treated at the Poison Control Center of Bach Mai Hospital from January 2018 to August 2022. Results: The median age was 34 (23 – 36), the most common in the 18 – 59 age group (76,7%), male/female ratio: 1,5/1. Geographic and occupational features were related to tin poisoning. The onset of symptoms and clinical features varied with neurological, circulatory, respiratory, digestive, and skin abnormalities; especially nerve damage accounted for a high rate in the group of tin poisoning (85,7%). Subclinical at the time of admission, brain damage on MRI in patients with tin toxicity (71,4%); copper (56,7%), mercury (25%). severe hypokalemia (19.0%), metabolic acidosis only seen in patients with tin toxicity (28,57%); anemia was highest in lead poisoning (45,5%). Treatment outcomes: complete recovery (68,3%), sequelae (30%), fatality (1,7%); Most of the clinical and subclinical abnormalities improved markedly after treatment, the difference was statistically significant (p < 0,05). Conclusion: Metal poisoning caused multi-organ damage, many sequelae; Tin poisoning was common in PVC recycling workers, brain damage had a high rate in patients with tin and copper poisoning.