MỐI LIÊN QUAN GIỮA ĐẶC ĐIỂMCỘNG HƯỞNG TỪ - GIẢI PHẪU BỆNH CƠ ĐÙI VÀ LÂM SÀNG, CẬN LÂM SÀNG Ở BỆNH NHÂN VIÊM ĐA CƠ, VIÊM DA CƠ TỰ MIỄN

Abstract

Objectives: 1/ Describe clinical, magnetic resonance, and anatomical characteristics of femoral muscle disease patients with polymyositis and autoimmune dermatomyositis at the Department of Musculoskeletal - Bach Mai Hospital. 2/ Find the relationship between clinical, magnetic resonance, and anatomical femoral myopathy in patients with polymyositis and autoimmune dermatomyositis at the Department of Musculoskeletal - Bach Mai Hospital in the researched patients. Subjects and research methods: A prospective, cross-sectional study was performed on patients diagnosed with polymyositis and dermatomyositis according to Bohan and Peter's criteria in 1975. The patients were examined for clinical examination, hematology, biochemistry, pathology, femoral magnetic resonance, and electromyography. Research results: 1) Clinical characteristics of muscle damage: mean muscle strength is 58.68 ± 7.30, mean muscle pain VAS is 5.38 ± 1.66, and average muscle inflammation accounts for the proportion. 46.6% high, and the main symptom of muscle weakness was 96.9%. 2) Characteristics of subclinical lesions: muscle edema is the primary lesion detected on MRI images of the thigh muscle at 65.6%, the late stage has muscle atrophy at 15.6%, and fat degeneration at 9.4%. Regarding muscle histopathology, the most common injury characteristics are inflammatory cell invasion, degeneration, regeneration, and proliferation, with 62.5%, 81.3%, 68.8%, and 78.1%, respectively. The rate of detection of muscle damage on MRI images of the thigh muscle correlates with increased CK concentration.