NGHIÊN CỨU GIÁ TRỊ TIÊN LƯỢNG GẦN CỦA CỘNG HƯỞNG TỪ SỌ NÃO Ở TRẺ SƠ SINH ĐỦ THÁNG CÓ BỆNH LÝ NÃO DO THIẾU MÁU CỤC BỘ/THIẾU OXY

Abstract

Objectives: To assess the short-term prognostic value of brain MRI in term newborns with hypoxic-ischemic encephalopathy. Subjects and research methods: Cross-sectional descriptive and cohort study on 94 term newborns with hypoxic-ischemic encephalopathy who was performed brain MRI within 2 weeks after birth. The relation between their short-term neurodevelopmental outcomes and and cerebral lesions on MRI was assessed. Results: The grey matter, cortex and white matter, cerebellum subscore, and total score were significantly associated with death or cerebral palsy in our study (OR:1,08-6,9, p <0.05). There is no relationship between either epilepsy or neurodevelopmental delay and cerebral lesions on MRI. The most valuable predictive subscore was basal ganglia subscore (AUC: 0,82-0,84), the cortical and white matter subscore is less valuable (AUC: 0,80-0,84), the cerebellar subscore has a limited value in predicting the death (AUC:0,61). The hemorrhagic subscore has no predictive value. Conclusion: The grey matter, cortex and white matter, cerebellum subscores, and total score were significantly associated with death or cerebral palsy. The most valuable predictive subscore was basal ganglia subscore. The hemorrhagic subscore has no predictive value.