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EVALUATION OF THE EFFECTIVENESS OF HEMODIALYSIS BY THE Kt/V INDEX AMONG PATIENTS WITH HEMODIALYSIS AT THE HEMODIALYSIS DEPARTMENT OF CHO RAY HOSPITAL
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Abstract
Evaluating the effectiveness of urea clearance in hemodialysis by the spKt/V indicator is necessary for treating patients with end-stage chronic kidney disease (ESRD). Multiple evaluation methods could support the specialists in choosing the best treatment methods for this disease. This study was conducted to evaluate the effectiveness of hemodialysis by comparing the spKt/V indicator in direct measurement on the machine to the calculation method according to the Daugridas formula. The cross-sectional descriptive study on 175 patients with ESRD undergoing hemodialysis at Cho Ray Hospital from January to June 2022 used the Willcoxon Signrank Test to compare the average spKt/V calculated by the two methods above. The results show that the average spKt/V calculated by the direct measurement on the machine (1.77 (1.5-2.06)) and the Daugridas formula (1.6 (1.36)-1.82)) were all within the recommended value. The Willcoxon Signrank Test illustrates a statistically significant difference in spKt/V in the two methods, while the Linear regression model shows a strong correlation with correlation coefficients R = 0.65 and R2 = 0.423 (p<0.001). Therefore, experts need to consider choosing an optimal method of measuring directly on the machine to evaluate and adjust parameters during the hemodialysis process in their professional interest to effectively treat the disease.
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Keywords
hemodialysis, end-stage chronic kidney disease, Kt/V indicator, Cho Ray Hospital
References
2. Trần Văn Vũ. Đánh giá tình trạng dinh dưỡng ở bệnh nhân suy thận mạn giai đoạn cuối chưa lọc thận. Y Học TP Hồ Chí Minh 2011;15(4):53-59.
3. Castellarnau A., Werner M., Günthner R., Jakob M. Real-time Kt/V determination by ultraviolet absorbance in spent dialysate: technique validation. Kidney Int, 2010;78(9):920-925.
4. Liu Qingquan, Wang Yiru, Chen Zhi, Guo Xiaolin, Lv Yongman. Age- and sex-specific reference intervals for blood urea nitrogen in Chinese general population. Scientific Reports, 2021;11(1):10058.
5. National Kidney Foundation. KDOQI Clinical Practice Guideline for Hemodialysis Adequacy: 2015 update", Am J Kidney Dis 2015; 66(5):884-930.
6. Romagnani P., Remuzzi G., Glassock R., et al. Chronic kidney disease. Nature reviews Disease primers, 2017;3:17088.
7. Sandra A, Wenke H, F Susan. Serum Albumin Level and Risk for Mortality and Hospitalization in Adolescents on Hemodialysis. Clinical Journal of the American Society of Nephrology 2008;3:759-767.
8. Somji Samina S., Ruggajo Pascal, Moledina Sibtain. Adequacy of Hemodialysis and Its Associated Factors among Patients Undergoing Chronic Hemodialysis in Dar es Salaam, Tanzania. Int J Nephrol, 2020:9863065-9863065.
9. Vart P., Powe N. R., McCulloch C. E., et al. National Trends in the Prevalence of Chronic Kidney Disease Among Racial/Ethnic and Socioeconomic Status Groups, 1988-2016. JAMA network open 2020; 3(7):e207932.