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Date Published: 28/12/2022
Abstract Views: 328
Views PDF: 167
DOI: https://doi.org/10.51298/vmj.v520i1.3746
Issue
Vol. 520 No. 1A (2022)
Section
Các bài báo
How to Cite
Thanh Lê, T. ., Ngọc Sơn, Đỗ ., & Quốc Chính, L. . (2022). PREDICTION FACTORS FOR THE SUCCESS OF HIGH-FLOW NASAL CANNULA OXYGEN THERAPY (HHFNC) IN PATIENTS WITH THE ACUTE EXACERBATION OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. Vietnam Medical Journal, 520(1A). https://doi.org/10.51298/vmj.v520i1.3746

PREDICTION FACTORS FOR THE SUCCESS OF HIGH-FLOW NASAL CANNULA OXYGEN THERAPY (HHFNC) IN PATIENTS WITH THE ACUTE EXACERBATION OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE

Trần Thanh Lê1, Đỗ Ngọc Sơn2,, Lương Quốc Chính3
1 Hanoi Medical University
2 Intensive Care Department, Bach Mai Hospital
3 Emergency Department, Bach Mai Hospital

Main Article Content

Abstract

Objectives: To evaluate of the prediction factors for the success of Heated and humidified high-flow nasal cannula (HHFNC) in patients with exacerbation of chronic obstructive pulmonary disease (COPD). Methods: Pre and post- intervention study on 32 patients with COPD exacerbation used HHFNC support. Results: the success rate with HHFNC was 65.6%. In the successful group, vital signs (heart rate, respiratory rate, SpO2 and blood pressure) and arterial blood gas (pH, PaO2, PaO2/FiO2) improved gradually (p<0.001). In the failure group, the pH decreased and PaCO2 increased significantly (p<0.05). Mechanical ventilation parameters (Flow, FiO2) decreased in the successful group and increased in the failure group during study period (p<0.001; p<0.05). PaCO2 with cut-off ≥ 62 mmHg (area under ROC curve, AUC = 0.8247), HACOR with cut-off ≥ 4 (AUC = 0.8636), ROX with cut-off ≥ 7,98 (AUC = 0.8030) provided high sensitivity, specificity, positive predictive value and negative predictive value. Conclusion: The successful prediction factors for HHFNC were PaCO2, HACOR and ROX at the initiation of the non-invasive ventilation for patients with the acute exacerbation of COPD.

Article Details

Keywords

Noninvasive mechanical ventilation, HHFNC, ACOPD

References

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